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Difference between revisions of "Nodular fasciitis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Nodular_fasciitis_-_intermed_mag.jpg | | Image = Nodular_fasciitis_-_intermed_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Nodular fasciitis. [[H&E stain]]. | | Caption = Nodular fasciitis. [[H&E stain]]. | ||
| Micro = usu. well-circumscribed, clusters of (non-pleomorphic) spindle cells, inflammation (lymphocytes), microcysts in cellular regions - uncommon, mitoses - common, [[extravasated RBC]]s. | | Micro = usu. well-circumscribed, clusters of (non-pleomorphic) spindle cells, inflammation (lymphocytes), microcysts in cellular regions - uncommon, mitoses - common, [[extravasated RBC]]s. | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = myxoid [[dermatofibrosarcoma protuberans]], cellular [[dermatofibroma]], [[desmoid-type fibromatosis]], other [[spindle cell lesions of the skin]] | ||
| Stains = | | Stains = | ||
| IHC = CD34 -ve, desmin -ve, SMA -ve, S-100 -ve, AE1/AE3 -ve. | | IHC = CD34 -ve, desmin -ve, SMA -ve, S-100 -ve, AE1/AE3 -ve. | ||
| Line 28: | Line 28: | ||
| ClinDDx = | | ClinDDx = | ||
}} | }} | ||
'''Nodular fasciitis''' is a benign [[soft tissue lesion]]. It should '''not''' to be confused with [[necrotizing fasciitis]]. | '''Nodular fasciitis''' is a benign [[soft tissue lesion]]. | ||
It should '''not''' to be confused with [[necrotizing fasciitis]]. | |||
==General== | ==General== | ||
*Benign. | *Benign. | ||
| Line 72: | Line 74: | ||
*Cellular [[dermatofibroma]]. | *Cellular [[dermatofibroma]]. | ||
*[[Desmoid-type fibromatosis]]. | *[[Desmoid-type fibromatosis]]. | ||
*Other [[spindle cell lesions of the skin]]. | |||
===Images=== | ===Images=== | ||
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*CD34 -ve. | *CD34 -ve. | ||
*Desmin -ve. | *Desmin -ve. | ||
*SMA - | *SMA +ve -- strong.{{fact}} | ||
*S-100 -ve. | *S-100 -ve. | ||
*AE1/AE3 -ve. | *AE1/AE3 -ve. | ||