Account-creators
1,040
edits
Difference between revisions of "Neuropathology tumours"
Jump to navigation
Jump to search
Minor rearrangement
Jensflorian (talk | contribs) m (→Infiltrative astrocytomas: typo) |
Jensflorian (talk | contribs) (Minor rearrangement) |
||
| Line 93: | Line 93: | ||
* [[Olfactory neuroblastoma]]. | * [[Olfactory neuroblastoma]]. | ||
* [[Endolymphatic sac tumour]]. | * [[Endolymphatic sac tumour]]. | ||
===Primary versus secondary=== | ===Primary versus secondary=== | ||
| Line 137: | Line 129: | ||
*[[Astrocytoma, IDH-mutant]]. | *[[Astrocytoma, IDH-mutant]]. | ||
*[[Glioblastoma]], IDH-wildtype. | *[[Glioblastoma]], IDH-wildtype. | ||
Notes: | |||
**Glial: "blends into brain"/gradual transition to non-tumour brain. | |||
====Non-infiltrative astrocytomas==== | ====Non-infiltrative astrocytomas==== | ||
| Line 142: | Line 137: | ||
**[[Pleomorphic xanthoastrocytoma]] | **[[Pleomorphic xanthoastrocytoma]] | ||
**[[Subependymal giant cell astrocytoma]]. | **[[Subependymal giant cell astrocytoma]]. | ||
====Cystic tumours==== | |||
DDx:<ref>URL: [http://path.upmc.edu/cases/case320/dx.html http://path.upmc.edu/cases/case320/dx.html]. Accessed on: 14 January 2012.</ref> | |||
*[[Pilocytic astrocytoma]]. | |||
*[[Pleomorphic xanthoastrocytoma]]. | |||
*[[Ganglioglioma]]. | |||
*[[Hemangioblastoma]]. | |||
*[[Craniopharyngioma]].<ref>URL: [http://www.pathologyoutlines.com/Cnstumor.html#cystsgeneral http://www.pathologyoutlines.com/Cnstumor.html#cystsgeneral]. Accessed on: 14 January 2012.</ref> | |||
Notes: | Notes: | ||
**Non-glial: no radiating glial processes. | **Non-glial: no radiating glial processes. | ||
*Rosenthal fibres within the tumour... often seen in [[pilocytic astrocytoma]]. | *Rosenthal fibres within the tumour... often seen in [[pilocytic astrocytoma]]. | ||
| Line 165: | Line 167: | ||
*WHO Grading is currently based on expected biologiocal behaviour without treatment. | *WHO Grading is currently based on expected biologiocal behaviour without treatment. | ||
**Grading does not reflect molecular divergent groups within a tumor class or response to therapy (Currently controversies in grading for IDH-mutant astrocytoma vs. IDH-wildtype astrocytoma).<ref>{{Cite journal | last1 = Louis | first1 = DN. | last2 = von Deimling | first2 = A. | title = Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zülch, the WHO… and Shakespeare. | journal = Acta Neuropathol | volume = | issue = | pages = | month = Aug | year = 2017 | doi = 10.1007/s00401-017-1765-z | PMID = 28801693 }}</ref> | **Grading does not reflect molecular divergent groups within a tumor class or response to therapy (Currently controversies in grading for IDH-mutant astrocytoma vs. IDH-wildtype astrocytoma).<ref>{{Cite journal | last1 = Louis | first1 = DN. | last2 = von Deimling | first2 = A. | title = Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zülch, the WHO… and Shakespeare. | journal = Acta Neuropathol | volume = | issue = | pages = | month = Aug | year = 2017 | doi = 10.1007/s00401-017-1765-z | PMID = 28801693 }}</ref> | ||
===By IHC=== | ===By IHC=== | ||