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Difference between revisions of "Neuropathology tumours"
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→Astrocytomas: +gliosarcoma
(→Atypical teratoid/rhabdoid tumour: +images) |
(→Astrocytomas: +gliosarcoma) |
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Notes: | Notes: | ||
*IDH1 and IDH2 mutations - better survival.<ref name=pmid20975057>{{cite journal |author=Houillier C, Wang X, Kaloshi G, ''et al.'' |title=IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas |journal=Neurology |volume=75 |issue=17 |pages=1560–6 |year=2010 |month=October |pmid=20975057 |doi=10.1212/WNL.0b013e3181f96282 |url=}}</ref> | *IDH1 and IDH2 mutations - better survival.<ref name=pmid20975057>{{cite journal |author=Houillier C, Wang X, Kaloshi G, ''et al.'' |title=IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas |journal=Neurology |volume=75 |issue=17 |pages=1560–6 |year=2010 |month=October |pmid=20975057 |doi=10.1212/WNL.0b013e3181f96282 |url=}}</ref> | ||
==Gliosarcoma== | |||
===General=== | |||
*Gliosarcoma = glioblastoma + sarcomatous component.<ref name=pmid20415184>{{cite journal |author=Ayadi L, Charfi S, Khabir A, ''et al.'' |title=[Cerebral gliosarcoma: clinico-pathologic study of 8 cases] |language=French |journal=Tunis Med |volume=88 |issue=3 |pages=142–6 |year=2010 |month=March |pmid=20415184 |doi= |url=}}</ref> | |||
===Microscopic=== | |||
Features: | |||
*Glioblastoma. | |||
*Sarcomatous component (one of the following):<ref name=pmid20415184/> | |||
**Fibrosarcoma. | |||
**Osteosarcoma. | |||
**Malignant fibrous histiocytoma. | |||
Image: [http://commons.wikimedia.org/wiki/File:Gliosarcoma_Histopathology_200x_EVG.jpg Gliosarcoma - elastic von Gieson (WC)]. | |||
==Pilocytic astrocytoma== | ==Pilocytic astrocytoma== | ||