Difference between revisions of "Neuropathology"

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Neuropathology (view source)

Revision as of 19:38, 14 January 2011

938 bytes added ,  19:38, 14 January 2011
→‎Hypoxic-ischemic encephalopathy: +hippocampal, +laminar necrosis
(→‎Pathology: more on CPM)
(→‎Hypoxic-ischemic encephalopathy: +hippocampal, +laminar necrosis)
Line 433: Line 433:
***Cavitation: bubbles/clear spaces where there should be none.
***Cavitation: bubbles/clear spaces where there should be none.
**CA2 neurons preserved/resistant.
**CA2 neurons preserved/resistant.
*Neurons of ''subiculum'' - usu. normal (as they are resistant to ischemic changes).
*Purkinje cell loss in the cerebellum and [[Bergmann gliosis]].
*Purkinje cell loss in the cerebellum and [[Bergmann gliosis]].
*"Anoxic neurons".<ref>URL: [http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html]. Accessed on: 12 July 2010.</ref>
*"Anoxic neurons".<ref>URL: [http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html]. Accessed on: 12 July 2010.</ref>
**Shrunken neurons with intensely eosinophilic cytoplasm and pyknotic (shrunken) nuclei.
**Shrunken neurons with intensely eosinophilic cytoplasm and pyknotic (shrunken) nuclei.
**Images:  
*Pseudolaminar necrosis - (uncontrolled) cell death in the cerebral cortex in a band-like pattern,<ref>Hypoxic and Ischemic Encephalopathy. neuropathology.neoucom.edu. Accessed on: 29 December 2010.</ref> with a relative preservation of cells immediately adjacent to the meninges.
***[http://www.neuropathologyweb.org/chapter2/images2/2-1HIE.jpg Anoxic neurons (neuropathologyweb.org)].
 
***[http://commons.wikimedia.org/wiki/File:Alzheimer_type_II_astrocyte_high_mag_cropped.jpg Anoxic neurons (WC)].
Images:  
***[http://moon.ouhsc.edu/kfung/iacp-olp/APAQ-Images/N1-MS-01-16.gif Anoxic neurons (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/N1-MS-01-16-Ans.htm http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/N1-MS-01-16-Ans.htm] and [http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/n1-ms-01.htm http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/n1-ms-01.htm]. Accessed on: 31 October 2010.</ref>
*Anoxic neurons:
**[http://www.neuropathologyweb.org/chapter2/images2/2-1HIE.jpg Anoxic neurons (neuropathologyweb.org)].
**[http://commons.wikimedia.org/wiki/File:Alzheimer_type_II_astrocyte_high_mag_cropped.jpg Anoxic neurons (WC)].
**[http://moon.ouhsc.edu/kfung/iacp-olp/APAQ-Images/N1-MS-01-16.gif Anoxic neurons (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/N1-MS-01-16-Ans.htm http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/N1-MS-01-16-Ans.htm] and [http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/n1-ms-01.htm http://moon.ouhsc.edu/kfung/iacp-olp/apaq-text/n1-ms-01.htm]. Accessed on: 31 October 2010.</ref>
*Hippocampal ischemic changes:
**[http://www.neuropathologyweb.org/chapter2/images2/2-hippoHIE.jpg Hippocampus in HIE (neuropathologyweb.org).<ref>URL: [http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html http://www.neuropathologyweb.org/chapter2/chapter2aHIE.html]. Accessed on: 14 January 2011.</ref>
*Pseudolaminar necrosis:
**[http://commons.wikimedia.org/wiki/File:Cortical_pseudolaminar_necrosis_-_lfb_-_very_low_mag.jpg Pseudolaminar necrosis - very low mag. (WC)].
**[http://commons.wikimedia.org/wiki/File:Cortical_pseudolaminar_necrosis_-_lfb_-_intermed_mag.jpg Pseudolaminar necrosis - intermed. mag. (WC)].
 
Notes:
*Neurons of ''subiculum'' in adults - usu. normal (as they are resistant to ischemic changes).


==Multiple sclerosis==
==Multiple sclerosis==
Michael
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