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Difference between revisions of "Neuroendocrine neoplasms"
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→IHC - generic: more
m (→Stomach) |
(→IHC - generic: more) |
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Key stains:<ref name=pmid17204019>{{Cite journal | last1 = Williams | first1 = GT. | title = Endocrine tumours of the gastrointestinal tract-selected topics. | journal = Histopathology | volume = 50 | issue = 1 | pages = 30-41 | month = Jan | year = 2007 | doi = 10.1111/j.1365-2559.2006.02570.x | PMID = 17204019 }}</ref> | Key stains:<ref name=pmid17204019>{{Cite journal | last1 = Williams | first1 = GT. | title = Endocrine tumours of the gastrointestinal tract-selected topics. | journal = Histopathology | volume = 50 | issue = 1 | pages = 30-41 | month = Jan | year = 2007 | doi = 10.1111/j.1365-2559.2006.02570.x | PMID = 17204019 }}</ref> | ||
*Chromogranin A +ve. | *Chromogranin A +ve. | ||
**Considered the most specific neuroendocrine stain.<ref name=pmid20182342>{{Cite journal | last1 = McCluggage | first1 = WG. | last2 = Kennedy | first2 = K. | last3 = Busam | first3 = KJ. | title = An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63. | journal = Am J Surg Pathol | volume = 34 | issue = 4 | pages = 525-32 | month = Apr | year = 2010 | doi = 10.1097/PAS.0b013e3181d1d457 | PMID = 20182342 }}</ref> | |||
*Synaptophysin +ve. | *Synaptophysin +ve. | ||
| Line 50: | Line 51: | ||
*CD56 +ve. | *CD56 +ve. | ||
*Ki-67 - useful for grading. | *Ki-67 - useful for grading. | ||
*PGP9.5.<ref name=pmid20182342/> | |||
Hormone products: | Hormone products: | ||