Difference between revisions of "Neurodegenerative diseases"

Jump to navigation Jump to search
(→‎Molecular: Update)
(→‎Clinical perspective: Poor clinical - molecular correlations)
Line 200: Line 200:


=Clinical perspective=
=Clinical perspective=
*Correlations between clinical signs and molecular can be poor.
**Example: The MAPT A152T gene mutation in the MAPT gene may cause clinical symptoms matching AD, [[Neurodegenerative diseases#Corticobasal degeneration|CBD]], [[Neurodegenerative diseases#Progressive supranuclear palys|PSP]] and  [[Neurodegenerative diseases#Lewy body disease|LBD]].
===Dementia general (mostly useless) DDx===
===Dementia general (mostly useless) DDx===
*[[Alzheimer's disease|Alzheimer's]] dementia - most common.
*[[Alzheimer's disease|Alzheimer's]] dementia - most common.