Nasopharyngeal angiofibroma
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| Nasopharyngeal angiofibroma | |
|---|---|
| Diagnosis in short | |
 Nasopharyngeal angiofibroma. H&E stain. | |
|
| |
| LM | fibroblastic cells with plump (near cuboidal) nuclei, fibrous stroma, abundant capillaries |
| Site | head and neck - nasopharynx |
|
| |
| Clinical history | male, adolescents young to adults, frequent nose bleeds |
| Prevalence | uncommon |
| Prognosis | benign |
| Treatment | surgical resection |
Nasopharyngeal angiofibroma is a benign lesion of the head and neck.
General
- Classically adolescent males with recurrent nose bleeds.
- Age range 8-41 in one series of 162 cases.[1]
- Can be subtyped by location into three groups.[2]
Microscopic
Features:[3]
- Fibroblastic cells with plump (near cuboidal) nuclei.
- Fibrous stroma.
- Abundant capillaries.
Images
Intermed. mag.
High mag.
Very high mag.
High mag.
See also
References
- ↑ Huang, Y.; Liu, Z.; Wang, J.; Sun, X.; Yang, L.; Wang, D. (Aug 2014). "Surgical management of juvenile nasopharyngeal angiofibroma: analysis of 162 cases from 1995 to 2012.". Laryngoscope 124 (8): 1942-6. doi:10.1002/lary.24522. PMID 24222212.
- ↑ Yi, Z.; Fang, Z.; Lin, G.; Lin, C.; Xiao, W.; Li, Z.; Cheng, J.; Zhou, A.. "Nasopharyngeal angiofibroma: a concise classification system and appropriate treatment options.". Am J Otolaryngol 34 (2): 133-41. doi:10.1016/j.amjoto.2012.10.004. PMID 23332298.
- ↑ Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 144. ISBN 978-1416002741.