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Difference between revisions of "Myxopapillary ependymoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg | | Image = Myxopapillary_ependymoma_-_very_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Myxopapillary ependymoma. [[ | | Caption = Myxopapillary ependymoma. [[HPS stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = Papillary tumor cells around vascular myxoid matrix | | Micro = Papillary tumor cells around vascular myxoid matrix | ||
| Subtypes = subtype of [[ependymoma]] | | Subtypes = subtype of [[ependymoma]] | ||
| LMDDx = [[ | | LMDDx = [[chordoma]], [[myxoid chondrosarcoma]], [[paraganglioma]], papillary [[adenocarcinoma]] | ||
| Stains = Alcian blue +ve | | Stains = Alcian blue +ve | ||
| IHC = GFAP +ve | | IHC = GFAP +ve | ||
| Line 40: | Line 40: | ||
==Gross== | ==Gross== | ||
* | *Soft. | ||
* | *Gray. | ||
* | *Discrete masses. | ||
* | *Often encapsulated. | ||
*Subtotal resected tumors may spread throughout the neuraxis. | *Subtotal resected tumors may spread throughout the neuraxis. | ||
| Line 51: | Line 51: | ||
</gallery> | </gallery> | ||
== | ==Microscopic== | ||
Features: | Features: | ||
*Papillary appearance. | *Papillary appearance. | ||
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*Microcysts. | *Microcysts. | ||
*Low mitotic activity. | *Low mitotic activity. | ||
Note: | Note: | ||
| Line 66: | Line 65: | ||
DDx: | DDx: | ||
* [[Chordoma]] | * [[Chordoma]]. | ||
* [[Myxoid chondrosarcoma]] | * [[Myxoid chondrosarcoma]]. | ||
* [[Paraganglioma]] | * [[Paraganglioma]]. | ||
* Papillary [[ | * Papillary [[adenocarcinoma]]. | ||
===Images=== | |||
<gallery> | <gallery> | ||
File:Myxopapillary_ependymoma.jpg | Mxyopapillary Ependymoma, HE Smear (AFIP) | File:Myxopapillary_ependymoma.jpg | Mxyopapillary Ependymoma, HE Smear (AFIP) | ||
File:Myxopapillary_ependymoma_-_intermed_mag.jpg | Mxyopapillary Ependymoma, low magnification (WC/Nephron) | File:Myxopapillary_ependymoma_-_intermed_mag.jpg | Mxyopapillary Ependymoma, low magnification (WC/Nephron) | ||
File:Myxopapillary_ependymoma-HE.jpg | Intermediate magnification (WC/jensflorian | File:Myxopapillary_ependymoma-HE.jpg | Intermediate magnification (WC/jensflorian) | ||
File:Myxopapillary_ependymoma_-_very_high_mag.jpg | High magnification (WC/Nephron) | File:Myxopapillary_ependymoma_-_very_high_mag.jpg | High magnification (WC/Nephron) | ||
File:Myxopapillary_ependymoma_HE_x40.jpg | Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian) | File:Myxopapillary_ependymoma_HE_x40.jpg | Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian) | ||
| Line 91: | Line 90: | ||
==Molecular== | ==Molecular== | ||
* Poorly characterized | * Poorly characterized. | ||
* No consistent abberations. | * No consistent abberations. | ||
==See also== | ==See also== | ||