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Difference between revisions of "Myopericytoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Myopericytoma_-_high_mag.jpg | |||
| Width = | |||
| Caption = Myopericytoma. [[H&E stain]]. | |||
| Micro = fascicular pattern (may be subtle) with compressed blood vessels (often thin walled & branching), increased peri-vascular cellularity; high cellularity; small bland unequally spaced epithelioid/spindle cells with moderate eosinophilic cytoplasm | |||
| Subtypes = | |||
| LMDDx = [[solitary fibrous tumour]], [[vascular tumours]] | |||
| Stains = | |||
| IHC = SMA +ve, H-caldesmon +ve, CD34 +ve (focal), EMA -ve, AE1/AE3 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[soft tissue]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Myopericytoma''', also '''glomangiopericytoma''', is a rare perivascular [[soft tissue lesions|soft tissue tumour]]. | '''Myopericytoma''', also '''glomangiopericytoma''', is a rare perivascular [[soft tissue lesions|soft tissue tumour]]. | ||
==General== | ==General== | ||
* | *Usually benign. | ||
*Typically in the distal extremities.<ref name=pmid21111282>{{cite journal |author=Zidane A, Arsalane A, Harkat A, ''et al.'' |title=[Myopericytoma: an uncommon chest wall tumor] |language=French |journal=Rev Mal Respir |volume=27 |issue=9 |pages=1089–91 |year=2010 |month=November |pmid=21111282 |doi=10.1016/j.rmr.2010.09.017 |url=}}</ref> | *Typically in the distal extremities.<ref name=pmid21111282>{{cite journal |author=Zidane A, Arsalane A, Harkat A, ''et al.'' |title=[Myopericytoma: an uncommon chest wall tumor] |language=French |journal=Rev Mal Respir |volume=27 |issue=9 |pages=1089–91 |year=2010 |month=November |pmid=21111282 |doi=10.1016/j.rmr.2010.09.017 |url=}}</ref> | ||
*Used to be classified as ''[[hemangiopericytoma]]'' (AKA solitary fibrous tumour). | |||
==Microscopic== | ==Microscopic== | ||
Features:<ref>{{cite journal |author=Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM |title=Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path |journal=Int. J. Surg. Pathol. |volume=19 |issue=2 |pages=247–51 |year=2011 |month=April |pmid=21474507 |doi=10.1177/1066896910381897 |url=}}</ref> | Features:<ref name=pmid21474507>{{cite journal |author=Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM |title=Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path |journal=Int. J. Surg. Pathol. |volume=19 |issue=2 |pages=247–51 |year=2011 |month=April |pmid=21474507 |doi=10.1177/1066896910381897 |url=}}</ref><ref name=Ref_WMSP615>{{Ref WMSP|615}}</ref> | ||
* | *Fascicular pattern - may be subtle - with: | ||
* | **Compressed blood vessels, often thin walled & branching. | ||
**Increased peri-vascular cellularity. | |||
*Cellular lesion: | *Cellular lesion: | ||
**Small bland unequally spaced epithelioid/spindle cells. | **Small bland unequally spaced epithelioid/spindle cells. | ||
| Line 18: | Line 49: | ||
DDx: | DDx: | ||
*[[Solitary fibrous tumour]]. | *[[Solitary fibrous tumour]]. | ||
*[[Vascular tumours]]. | |||
*[[Angioleiomyoma]].<ref name=pmid16330949>{{cite journal |author=Mentzel T, Dei Tos AP, Sapi Z, Kutzner H |title=Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases |journal=Am. J. Surg. Pathol. |volume=30 |issue=1 |pages=104–13 |year=2006 |month=January |pmid=16330949 |doi= |url=}}</ref> | |||
Images: | ===Images=== | ||
<gallery> | |||
Image:Myopericytoma - low mag.jpg | Myopericytoma - low mag. (WC) | |||
Image:Myopericytoma - intermed mag.jpg | Myopericytoma - intermed. mag. (WC) | |||
Image:Myopericytoma - high mag.jpg | Myopericytoma - high mag. (WC) | |||
Image:Myopericytoma - b - high mag.jpg | Myopericytoma - high mag. (WC) | |||
Image:Myopericytoma - very high mag.jpg | Myopericytoma - very high mag. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
* | Features:<ref name=Ref_WMSP615>{{Ref WMSP|615}}</ref><ref name=eihc_myo>URL: [http://e-immunohistochemistry.info/web/Myopericytoma.htm http://e-immunohistochemistry.info/web/Myopericytoma.htm]. Accessed on: 6 May 2011.</ref> | ||
*CD34 -ve. | *SMA +ve. | ||
*H-caldesmon +ve. | |||
*CD34 +ve (focal). | |||
Others:<ref name=eihc_myo>URL: [http://e-immunohistochemistry.info/web/Myopericytoma.htm http://e-immunohistochemistry.info/web/Myopericytoma.htm]. Accessed on: 6 May 2011.</ref> | |||
*AE1/AE3 -ve. | |||
*EMA -ve. | |||
==See also== | |||
*[[Glomus tumour]] - the other perivascular tumour. | |||
*[[Soft tissue lesions]]. | |||
==References== | ==References== | ||