Difference between revisions of "Myofibroma"

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*[[Neurofibroma]].
*[[Neurofibroma]].
*[[Leiomyoma]].
*[[Leiomyoma]].
===Images===
www:
*[http://casereports.bmj.com/content/2014/bcr-2014-203977/F5.large.jpg Myofibroma (bmj.com)].<ref name=pmid25178888>{{Cite journal  | last1 = Rai | first1 = B. | last2 = Ludusan | first2 = E. | last3 = McGovern | first3 = B. | last4 = Sharif | first4 = F. | title = Mandibular swelling in a 5-year-old child--mandibular myofibroma. | journal = BMJ Case Rep | volume = 2014 | issue =  | pages =  | month =  | year = 2014 | doi = 10.1136/bcr-2014-203977 | PMID = 25178888 }}</ref>


==IHC==
==IHC==

Latest revision as of 00:08, 16 November 2014

Myofibroma is a soft tissue lesion in the group fibroblastic/myofibroblastic tumours.

General

  • Benign.
  • Often < 2 years old; however, may be seen in adults.
  • Not common.[1]

Gross

  • Classically (oral) locations: tongue, buccal mucosa, lip.[1]

Microscopic

Features:[1]

  • Spindle cells with:
    • Tapering nuclei.
    • Eosinophilic cytoplasm.

Note:

DDx:

Images

www:

IHC

Features:[1]

  • Vimentin +ve.
  • SMA +ve.
  • S-100 -ve,

See also

References

  1. 1.0 1.1 1.2 1.3 Brasileiro, BF.; Martins-Filho, PR.; Piva, MR.; da Silva, LC.; Nonaka, CF.; Miguel, MC. (Jul 2010). "Myofibroma of the oral cavity. A rare spindle cell neoplasm.". Med Oral Patol Oral Cir Bucal 15 (4): e596-600. PMID 20038894. http://www.medicinaoral.com/pubmed/medoralv15_i4_p596.pdf.
  2. Dray MS, McCarthy SW, Palmer AA, et al. (January 2006). "Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases". J. Clin. Pathol. 59 (1): 67–73. doi:10.1136/jcp.2005.028704. PMC 1860256. PMID 16394283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860256/.
  3. Rai, B.; Ludusan, E.; McGovern, B.; Sharif, F. (2014). "Mandibular swelling in a 5-year-old child--mandibular myofibroma.". BMJ Case Rep 2014. doi:10.1136/bcr-2014-203977. PMID 25178888.