Difference between revisions of "Mucin"
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==Significance== | ==Significance== | ||
*It may be associated with [[cancer]]. | *It may be associated with [[cancer]]. | ||
*Mucin without malignant cells is ''not'' significant.<ref name=pmid21164296>PMID 21164296.</ref> | *Mucin without malignant cells is ''not'' significant.<ref name=pmid21164296>{{Cite journal | last1 = Shia | first1 = J. | last2 = McManus | first2 = M. | last3 = Guillem | first3 = JG. | last4 = Leibold | first4 = T. | last5 = Zhou | first5 = Q. | last6 = Tang | first6 = LH. | last7 = Riedel | first7 = ER. | last8 = Weiser | first8 = MR. | last9 = Paty | first9 = PB. | title = Significance of acellular mucin pools in rectal carcinoma after neoadjuvant chemoradiotherapy. | journal = Am J Surg Pathol | volume = 35 | issue = 1 | pages = 127-34 | month = Jan | year = 2011 | doi = 10.1097/PAS.0b013e318200cf78 | PMID = 21164296 }}</ref> | ||
===Mucin extravasation=== | |||
*A phenomenon seen in pedunculated [[colorectal polyps]] - that may lead to a misdiagnosis of [[mucinous carcinoma]].<ref name=Ref_Odze512>{{Ref Odze|512}}</ref> | |||
**Classically in the sigmoid colon and descending colon. | |||
DDx: | |||
*[[Mucinous carcinoma]] - should do [[levels]] to reduce the chance of under-sampling. | |||
==See also== | ==See also== | ||
*[[Mucinous carcinoma]]. | *[[Mucinous carcinoma]]. | ||
*[[Pseudoinvasion]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Stuff]] | [[Category:Stuff]] | ||
Latest revision as of 09:48, 14 August 2012
Mucin an important thingy in pathology, as it may be associated with cancer, i.e. mucinous carcinoma. It should not be confused with mucous.
Significance
Mucin extravasation
- A phenomenon seen in pedunculated colorectal polyps - that may lead to a misdiagnosis of mucinous carcinoma.[2]
- Classically in the sigmoid colon and descending colon.
DDx:
- Mucinous carcinoma - should do levels to reduce the chance of under-sampling.
See also
References
- ↑ Shia, J.; McManus, M.; Guillem, JG.; Leibold, T.; Zhou, Q.; Tang, LH.; Riedel, ER.; Weiser, MR. et al. (Jan 2011). "Significance of acellular mucin pools in rectal carcinoma after neoadjuvant chemoradiotherapy.". Am J Surg Pathol 35 (1): 127-34. doi:10.1097/PAS.0b013e318200cf78. PMID 21164296.
- ↑ Odze, Robert D.; Goldblum, John R. (2009). Surgical pathology of the GI tract, liver, biliary tract and pancreas (2nd ed.). Saunders. pp. 512. ISBN 978-1416040590.