Difference between revisions of "Molecular pathology"

Molecular pathology (view source)

574 bytes added , 14:19, 4 May 2011

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 *Southern blot.
 **Analysis of proteins.
+*Amplification-refractory mutation system (ARMS):<ref name=pmid18428319>{{cite journal |author=Little S |title=Amplification-refractory mutation system (ARMS) analysis of point mutations |journal=Curr Protoc Hum Genet |volume=Chapter 9 |issue= |pages=Unit 9.8 |year=2001 |month=May |pmid=18428319 |doi=10.1002/0471142905.hg0908s07 |url=}}</ref>
+**Technique for finding a (specific) single base change.
+***The (PCR) primers are designed bind to mutated sequence.
+****If the mutation is present a PCR product is seen.
+****If the mutation is absent no PCR product is seen.
 ===Tests===