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Difference between revisions of "Mixed epithelial and stromal tumour of the kidney"
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Mixed epithelial and stromal tumour of the kidney (view source)
Revision as of 15:50, 3 March 2020
, 15:50, 3 March 2020→Microscopic
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| Caption = Mixed epithelial stromal tumour of kidney. [[H&E stain]]. | | Caption = Mixed epithelial stromal tumour of kidney. [[H&E stain]]. | ||
| Synonyms = mixed epithelial and stromal tumour family (term recommended in WHO 2016 classification) | | Synonyms = [[mixed epithelial and stromal tumour family]] (term recommended in WHO 2016 classification) | ||
| Micro = cysts lined by simple epithelium with hobnailing, stroma has an ovarian look (basophilic, spindle cells) | | Micro = cysts lined by simple epithelium with hobnailing, stroma has an ovarian look (basophilic, spindle cells) | ||
| Subtypes = on a spectrum with [[cystic nephroma, adult type]] | | Subtypes = on a spectrum with [[cystic nephroma, adult type]] | ||
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Turbiner ''et al.''<ref name=pmid17414095>{{Cite journal | last1 = Turbiner | first1 = J. | last2 = Amin | first2 = MB. | last3 = Humphrey | first3 = PA. | last4 = Srigley | first4 = JR. | last5 = De Leval | first5 = L. | last6 = Radhakrishnan | first6 = A. | last7 = Oliva | first7 = E. | title = Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term. | journal = Am J Surg Pathol | volume = 31 | issue = 4 | pages = 489-500 | month = Apr | year = 2007 | doi = 10.1097/PAS.0b013e31802bdd56 | PMID = 17414095 }}</ref> came-up with a cheeky term for the the tumour family (''[[renal epithelial and stromal tumour]]'', abbreviated ''REST'') that didn't catch on. | Turbiner ''et al.''<ref name=pmid17414095>{{Cite journal | last1 = Turbiner | first1 = J. | last2 = Amin | first2 = MB. | last3 = Humphrey | first3 = PA. | last4 = Srigley | first4 = JR. | last5 = De Leval | first5 = L. | last6 = Radhakrishnan | first6 = A. | last7 = Oliva | first7 = E. | title = Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term. | journal = Am J Surg Pathol | volume = 31 | issue = 4 | pages = 489-500 | month = Apr | year = 2007 | doi = 10.1097/PAS.0b013e31802bdd56 | PMID = 17414095 }}</ref> came-up with a cheeky term for the the tumour family (''[[renal epithelial and stromal tumour]]'', abbreviated ''REST'') that didn't catch on. | ||
This kidney tumour should '''not''' be confused with ''mixed epithelial-stromal tumour of seminal vesicle''.<ref name=pmid25664946>{{Cite journal | last1 = Reikie | first1 = BA. | last2 = Yilmaz | first2 = A. | last3 = Medlicott | first3 = S. | last4 = Trpkov | first4 = K. | title = Mixed epithelial-stromal tumor (MEST) of seminal vesicle: a proposal for unified nomenclature. | journal = Adv Anat Pathol | volume = 22 | issue = 2 | pages = 113-20 | month = Mar | year = 2015 | doi = 10.1097/PAP.0000000000000057 | PMID = 25664946 }}</ref> | |||
==General== | ==General== | ||
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*[[Cystic nephroma, pediatric type]] - more cystic. | *[[Cystic nephroma, pediatric type]] - more cystic. | ||
*[[Tubulocystic renal cell carcinoma]] - has high grade nucleoli. | *[[Tubulocystic renal cell carcinoma]] - has high grade nucleoli. | ||
*[[Papillary renal cell carcinoma]] with MEST-like stroma.<ref name=pmid31862520>{{cite journal |authors=Rogala J, Kojima F, Alaghehbandan R, Agaimy A, Martinek P, Ondic O, Ulamec M, Sperga M, Michalova K, Pivovarcikova K, Pitra T, Hora M, Ferak I, Marečková J, Michal M, Hes O |title=Papillary renal cell carcinoma with prominent spindle cell stroma - tumor mimicking mixed epithelial and stromal tumor of the kidney: Clinicopathologic, morphologic, immunohistochemical and molecular genetic analysis of 6 cases |journal=Ann Diagn Pathol |volume=44 |issue= |pages=151441 |date=February 2020 |pmid=31862520 |doi=10.1016/j.anndiagpath.2019.151441 |url=}}</ref> | |||
===Images=== | ===Images=== | ||