Miscellaneous ovarian tumours

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The article collects miscellaneous ovarian tumours, as per the WHO classification.[1]

Ovarian small cell carcinoma of the pulmonary type

See: Small cell carcinoma.

Ovarian small cell carcinoma of the hypercalcemic type

  • AKA small cell carcinoma, hypercalcemic type, AKA small cell carcinoma of the ovary, hypercalcemic type.

General

  • Hypercalcemia.[2]
  • Rare.

Microscopic

Features:[2]

  • Small cell carcinoma.
  • Follicle-like spaces.

DDx:

Images:

IHC

Features:[3]

  • WT-1 +ve.
  • TTF-1 -ve.
  • HPV -ve.
  • p16 +ve/-ve.

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 403. ISBN 978-0781765275.
  2. 2.0 2.1 Young, RH.; Oliva, E.; Scully, RE. (Nov 1994). "Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases.". Am J Surg Pathol 18 (11): 1102-16. PMID 7943531.
  3. Carlson, JW.; Nucci, MR.; Brodsky, J.; Crum, CP.; Hirsch, MS. (Sep 2007). "Biomarker-assisted diagnosis of ovarian, cervical and pulmonary small cell carcinomas: the role of TTF-1, WT-1 and HPV analysis.". Histopathology 51 (3): 305-12. doi:10.1111/j.1365-2559.2007.02790.x. PMID 17727473.