Microphthalmia transcription factor
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Microphthalmia transcription factor, abbreviated MITF, is a common immunostain in the diagnosis of malignant melanoma.
| Microphthalmia transcription factor | |
|---|---|
| Immunostain in short | |
| Abbreviation | MITF |
| Use | malignant melanoma |
| Positive | nuclear stain |
General
MITF is a in the microphthalmia (abbreviated MiT) subfamily of transcription factors that also inclues TFE3, TFEB, TFEC.[1]
References
- ↑ Xie L, Zhang Y, Wu CL (October 2019). "Microphthalmia family of transcription factors associated renal cell carcinoma". Asian J Urol 6 (4): 312–320. doi:10.1016/j.ajur.2019.04.003. PMC 6872788. PMID 31768316. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872788/.