Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma

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Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma is a pattern of endometrioid endometrial carcinoma. Microcystic elongated and fragmented glands is typically abbreviated as MELF.[1]

Microscopic

Features:

  • Stromal mucin.[2]
    • Mucinous differentiation common.
  • Lymphovascular invasion

See also

References

  1. ↑ Euscher, E.; Fox, P.; Bassett, R.; Al-Ghawi, H.; Ali-Fehmi, R.; Barbuto, D.; Djordjevic, B.; Frauenhoffer, E. et al. (Nov 2013). "The pattern of myometrial invasion as a predictor of lymph node metastasis or extrauterine disease in low-grade endometrial carcinoma.". Am J Surg Pathol 37 (11): 1728-36. doi:10.1097/PAS.0b013e318299f2ab. PMID 24061515.
  2. ↑ Stewart CJ, Brennan BA, Leung YC, Little L (2009). "MELF pattern invasion in endometrial carcinoma: association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion". Pathology 41 (5): 454–9. doi:10.1080/00313020903041135. PMID 19900084.
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