Difference between revisions of "Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma"

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'''Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma''' is a pattern of [[endometrioid endometrial carcinoma]].  ''Microcystic elongated and fragmented glands'' is typically abbreviated as '''MELF'''.<ref name=pmid24061515>{{Cite journal  | last1 = Euscher | first1 = E. | last2 = Fox | first2 = P. | last3 = Bassett | first3 = R. | last4 = Al-Ghawi | first4 = H. | last5 = Ali-Fehmi | first5 = R. | last6 = Barbuto | first6 = D. | last7 = Djordjevic | first7 = B. | last8 = Frauenhoffer | first8 = E. | last9 = Kim | first9 = I. | title = The pattern of myometrial invasion as a predictor of lymph node metastasis or extrauterine disease in low-grade endometrial carcinoma. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1728-36 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e318299f2ab | PMID = 24061515 }}</ref>
'''Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma''' is a pattern of [[endometrioid endometrial carcinoma]].  ''Microcystic elongated and fragmented glands'' is typically abbreviated as '''MELF'''.<ref name=pmid24061515>{{Cite journal  | last1 = Euscher | first1 = E. | last2 = Fox | first2 = P. | last3 = Bassett | first3 = R. | last4 = Al-Ghawi | first4 = H. | last5 = Ali-Fehmi | first5 = R. | last6 = Barbuto | first6 = D. | last7 = Djordjevic | first7 = B. | last8 = Frauenhoffer | first8 = E. | last9 = Kim | first9 = I. | title = The pattern of myometrial invasion as a predictor of lymph node metastasis or extrauterine disease in low-grade endometrial carcinoma. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1728-36 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e318299f2ab | PMID = 24061515 }}</ref>
==Microscopic==
Features:
*Stromal mucin.<ref name=pmid19900084>{{cite journal |authors=Stewart CJ, Brennan BA, Leung YC, Little L |title=MELF pattern invasion in endometrial carcinoma: association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion |journal=Pathology |volume=41 |issue=5 |pages=454–9 |date=2009 |pmid=19900084 |doi=10.1080/00313020903041135 |url=}}</ref>
**Mucinous differentiation common.
*Lymphovascular invasion


==See also==
==See also==

Revision as of 14:53, 5 March 2020

Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma is a pattern of endometrioid endometrial carcinoma. Microcystic elongated and fragmented glands is typically abbreviated as MELF.[1]

Microscopic

Features:

  • Stromal mucin.[2]
    • Mucinous differentiation common.
  • Lymphovascular invasion

See also

References

  1. Euscher, E.; Fox, P.; Bassett, R.; Al-Ghawi, H.; Ali-Fehmi, R.; Barbuto, D.; Djordjevic, B.; Frauenhoffer, E. et al. (Nov 2013). "The pattern of myometrial invasion as a predictor of lymph node metastasis or extrauterine disease in low-grade endometrial carcinoma.". Am J Surg Pathol 37 (11): 1728-36. doi:10.1097/PAS.0b013e318299f2ab. PMID 24061515.
  2. Stewart CJ, Brennan BA, Leung YC, Little L (2009). "MELF pattern invasion in endometrial carcinoma: association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion". Pathology 41 (5): 454–9. doi:10.1080/00313020903041135. PMID 19900084.