Difference between revisions of "Mesonephric remnant of the prostate gland"

From Libre Pathology
Jump to navigation Jump to search
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Mesonephric remnant hyperplasia of the prostate gland''', also '''mesonephric remnant''', is rare benign finding in the [[prostate gland]] that can be confused with [[malignancy]].
'''Mesonephric remnant of the prostate gland''', also '''mesonephric remnant''', is rare benign finding in the [[prostate gland]] that can be confused with [[prostate carcinoma]].
 
This article also deals with '''mesonephric remnant hyperplasia'''.


==General==
==General==
*Very rare.<ref name=pmid21606823>{{Cite journal  | last1 = Chen | first1 = YB. | last2 = Fine | first2 = SW. | last3 = Epstein | first3 = JI. | title = Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy. | journal = Am J Surg Pathol | volume = 35 | issue = 7 | pages = 1054-61 | month = Jul | year = 2011 | doi = 10.1097/PAS.0b013e318218df97 | PMID = 21606823 }}</ref> ~ 0.6% incidence in a series of almost 700 [[TURP]] specimens.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }}</ref>
*Very rare<ref name=pmid21606823>{{Cite journal  | last1 = Chen | first1 = YB. | last2 = Fine | first2 = SW. | last3 = Epstein | first3 = JI. | title = Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy. | journal = Am J Surg Pathol | volume = 35 | issue = 7 | pages = 1054-61 | month = Jul | year = 2011 | doi = 10.1097/PAS.0b013e318218df97 | PMID = 21606823 }}</ref> ~ 0.6% incidence in a series of almost 700 [[TURP]] specimens.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }}</ref>
*Can mimic prostate carcinoma.<ref name=pmid19917478>{{Cite journal  | last1 = Yacoub | first1 = M. | last2 = Milin | first2 = S. | last3 = Irani | first3 = J. | last4 = Fromont | first4 = G. | title = Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer. | journal = Ann Diagn Pathol | volume = 13 | issue = 6 | pages = 402-4 | month = Dec | year = 2009 | doi = 10.1016/j.anndiagpath.2009.03.008 | PMID = 19917478 }}</ref>
*Can mimic prostate carcinoma.<ref name=pmid19917478>{{Cite journal  | last1 = Yacoub | first1 = M. | last2 = Milin | first2 = S. | last3 = Irani | first3 = J. | last4 = Fromont | first4 = G. | title = Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer. | journal = Ann Diagn Pathol | volume = 13 | issue = 6 | pages = 402-4 | month = Dec | year = 2009 | doi = 10.1016/j.anndiagpath.2009.03.008 | PMID = 19917478 }}</ref>


Line 10: Line 12:
**Scant-to-moderate cytoplasm.<ref name=pmid12861057/>
**Scant-to-moderate cytoplasm.<ref name=pmid12861057/>
**Small/indistinct nucleoli.
**Small/indistinct nucleoli.
Note:
*May look like Gleason pattern 3 adenocarcinoma.


DDx:<ref name=pmid21606823/>
DDx:<ref name=pmid21606823/>
Line 21: Line 26:
==IHC==
==IHC==
Features:<ref name=pmid21606823/>
Features:<ref name=pmid21606823/>
*PAX8 +ve.
*[[PAX8]] +ve.
*PSA -ve (all).
*[[PSA]] -ve (all).
*PSAP -ve.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }</ref>
*[[PSAP]] -ve.<ref name=pmid12861057/>
*CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
*[[CK34betaE12]] +ve/-ve (diffuse +ve in 4/7 cases)
*p63 -ve.
*[[p63]] -ve.
*AMACR +ve (focal).
*[[AMACR]] +ve (focal).


==See also==
==See also==
*[[Prostate gland]].
*[[Prostate gland]].
*[[Prostate cancer]].
*[[Prostate cancer]].
*[[Nephrogenic adenoma]].


==References==
==References==

Latest revision as of 14:52, 4 August 2022

Mesonephric remnant of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with prostate carcinoma.

This article also deals with mesonephric remnant hyperplasia.

General

  • Very rare[1] ~ 0.6% incidence in a series of almost 700 TURP specimens.[2]
  • Can mimic prostate carcinoma.[3]

Microscopic

Features:[1]

  • Small glands in a lobular arrangement composed of cuboidal cells with:
    • Scant-to-moderate cytoplasm.[2]
    • Small/indistinct nucleoli.

Note:

  • May look like Gleason pattern 3 adenocarcinoma.

DDx:[1]

Images

www:

IHC

Features:[1]

See also

References

  1. 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.
  2. 2.0 2.1 2.2 2.3 Bostwick, DG.; Qian, J.; Ma, J.; Muir, TE. (Jul 2003). "Mesonephric remnants of the prostate: incidence and histologic spectrum.". Mod Pathol 16 (7): 630-5. doi:10.1097/01.MP.0000074733.10777.78. PMID 12861057.
  3. Yacoub, M.; Milin, S.; Irani, J.; Fromont, G. (Dec 2009). "Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer.". Ann Diagn Pathol 13 (6): 402-4. doi:10.1016/j.anndiagpath.2009.03.008. PMID 19917478.