Difference between revisions of "Meningioma"

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*Claudin-1 - new kid on the block: +ve in meningioma, but low [[sensitivity]].
*Claudin-1 - new kid on the block: +ve in meningioma, but low [[sensitivity]].


===Standard work-up (UHN)===
===A standard work-up===
*Ki-67 >5-10% - predicts re-occurrence.<ref>Croul, SE. 8 November 2010.</ref>
*Ki-67 >5-10% - predicts re-occurrence.<ref>Croul, SE. 8 November 2010.</ref>
*PR (progesterone receptor) +ve in > 80% of meningiomas.<ref>{{Cite journal  | last1 = Takei | first1 = H. | last2 = Buckleair | first2 = LW. | last3 = Powell | first3 = SZ. | title = Immunohistochemical expression of apoptosis regulating proteins and sex hormone receptors in meningiomas. | journal = Neuropathology | volume = 28 | issue = 1 | pages = 62-8 | month = Feb | year = 2008 | doi = 10.1111/j.1440-1789.2007.00852.x | PMID = 18021195 }}</ref>  
*PR (progesterone receptor) +ve in > 80% of meningiomas.<ref>{{Cite journal  | last1 = Takei | first1 = H. | last2 = Buckleair | first2 = LW. | last3 = Powell | first3 = SZ. | title = Immunohistochemical expression of apoptosis regulating proteins and sex hormone receptors in meningiomas. | journal = Neuropathology | volume = 28 | issue = 1 | pages = 62-8 | month = Feb | year = 2008 | doi = 10.1111/j.1440-1789.2007.00852.x | PMID = 18021195 }}</ref>  
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