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Difference between revisions of "Meningioma"
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*Thick-walled blood vessels, usually prominent. | *Thick-walled blood vessels, usually prominent. | ||
*Calcification. | *Calcification. | ||
Images: | Images: | ||
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Notes: | Notes: | ||
*May involute into benign sclerotic tissue.<ref>URL: [http://radiographics.rsna.org/content/23/3/785.long http://radiographics.rsna.org/content/23/3/785.long]. Accessed on: 3 November 2010.</ref> | *May involute into benign sclerotic tissue.<ref>URL: [http://radiographics.rsna.org/content/23/3/785.long http://radiographics.rsna.org/content/23/3/785.long]. Accessed on: 3 November 2010.</ref> | ||
===Subtypes=== | |||
Many subtypes exist.<ref name=Ref_PSNP194>{{Ref PSNP|194}}</ref> | |||
Grade I: | |||
*Meningothelial. | |||
**Most common. | |||
**Microscopic: syncytial, nuclear clearing (pseudoinclusions). | |||
*Fibrous (fibroblastic). | |||
**Not collagen but looks like it. (It is really laminin or fibronectin). | |||
*Transistional. | |||
**Rare. | |||
*Psammomatous. | |||
**Microscopic: Psammoma bodies. | |||
*Angiomatous (vascular). | |||
**May bleed like stink. | |||
*Microcystic. | |||
**Microscopic: cystic appearance. | |||
*Secretory. | |||
**Microscopic: intracytoplasmic inclusions that are CEA +ve and PAS +ve. | |||
**Assoc. with brain edema; may have a work outcome. | |||
*Lymphoplasmacyte-rich. | |||
*Metaplastic. | |||
**Much talked about... but very rare. | |||
**Microscopic: cartilage or bone formation. | |||
Grade II: | |||
*Invasive (invades the brain). | |||
*Clear cell. | |||
**Microscopic: clear cells - contain glycogen (PAS +ve). | |||
**Epi.: usu. spinal cord.<ref>{{Ref PSNP|200}}</ref> | |||
*Chordoid (chordoma-like). | |||
**Microscopic: myxoid appearance. | |||
Grade III: | |||
*Papillary. | |||
**Microscopic: true papillae. | |||
*Rhaboid. | |||
**Microscopic: rhadoid appearance (abundant cytoplasm | |||
===Histomorphologic grading=== | ===Histomorphologic grading=== | ||