Medullomyoblastoma

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Medullomyoblastoma is a depreceated tumour entity. It was categorized in the WHO 1997 and WHO 2000 classfication as rare embryonal tumour with primitive neuroectodermal and striated muscle component (ICD-O code 9472/3). The tumour was removed as distinct entity in the WHO 2007 classification and is now considered a variant of medulloblastoma.[1] Some authors report MYC amplification in these tumours. [2][3]


Image

Exemplary image in [ pubcan.org [1]]


See also

References

  1. Smolle, E.; Al-Qubati, S.; Stefanits, H.; Haberler, C.; Kleinert, R.; Haybaeck, J. (Nov 2012). "Medullomyoblastoma: a case report and literature review of a rare tumor entity.". Anticancer Res 32 (11): 4939-44. PMID 23155263.
  2. Lindberg, E.; Persson, A.; Øra, I.; Mertens, F.; Englund, E.; Gisselsson, D. (Dec 2007). "Concurrent gain of 17q and the MYC oncogene in a medullomyoblastoma.". Neuropathology 27 (6): 556-60. doi:10.1111/j.1440-1789.2007.00810.x. PMID 18021376.
  3. Wright, KD.; von der Embse, K.; Coleman, J.; Patay, Z.; Ellison, DW.; Gajjar, A. (Sep 2012). "Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases.". Pediatr Blood Cancer 59 (3): 561-4. doi:10.1002/pbc.24002. PMID 22147345.