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Difference between revisions of "Medullary breast carcinoma"
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Medullary breast carcinoma (view source)
Revision as of 11:36, 8 September 2016
, 11:36, 8 September 2016no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = all required: (1) lesion has well-circumscribed border, (2) syncytial growth pattern, (3) lymphocytic infiltrate, (4) high nuclear grade (as per Nottingham grading system), (5) no tubule formation | |||
| Subtypes = | |||
| LMDDx = [[Invasive ductal carcinoma of the breast|Invasive ductal carcinoma]] with medullary features | |||
| Stains = | |||
| IHC = ER -ve, PR -ve, HER2 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = [[breast grossing]] | |||
| Staging = [[breast cancer staging]] | |||
| Site = [[breast]] - see ''[[invasive breast cancer]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = better than NST | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Medullary breast carcinoma''' is an uncommon form of [[invasive breast carcinoma]]. | '''Medullary breast carcinoma''' is an uncommon form of [[invasive breast carcinoma]]. | ||
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Epidemiology: | Epidemiology: | ||
*Thought to have a better prognosis that no special type (NST). | *Thought to have a better prognosis that no special type (NST). | ||
*May be associated with a BRCA1 mutation. | *May be associated with a [[BRCA1]] mutation. | ||
==Gross== | ==Gross== | ||
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#High nuclear grade (as per Nottingham grading system). | #High nuclear grade (as per Nottingham grading system). | ||
#No tubule formation. | #No tubule formation. | ||
DDx: | |||
*[[Invasive ductal carcinoma of the breast|Invasive ductal carcinoma]] with medullary features. | |||
==Images== | |||
<gallery> | |||
Image:Breast MedullaryCarcinoma (2) PA.JPG|Breast - Medullary Carcinoma - low power (SKB) | |||
Image:Breast MedullaryCarcinoma TripleNegative LP PA.JPG|Breast - Medullary Carcinoma - medium power (SKB) | |||
Image:Breast MedullaryCarcinoma TripleNegative HP PA.JPG|Breast - Medullary Carcinoma - high power (SKB) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Invasive breast | [[Category:Invasive breast cancer]] | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||