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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 15:57, 29 October 2011
, 15:57, 29 October 2011→Important terms/process related: more
m (→Classification) |
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*Kappa. | *Kappa. | ||
*Lambda. | *Lambda. | ||
====Negative immunofluorescence== | |||
*Excludes all immune complex associated disease. | |||
Seen in: | |||
* [[Minimal change disease]]. | |||
* [[Focal segmental glomerulosclerosis]]. | |||
====Positive immunofluorescence==== | |||
*Positive immunofluorescence is usually diagnostic. | |||
Seen in: | |||
*[[Lupus]] - granular, "full house". | |||
*[[IgA nephropathy]] - branching IgA +ve. | |||
*[[Dense deposit disease]] (DDD) - linear C3 with mesangial rings; IgG -ve, IgA -ve. | |||
*Immune complex disease (primary and secondary) - thick granular deposits. | |||
*[[Anti-glomerular basement membrane disease]] - linear IgG. | |||
*[[Goodpasture syndrome]] - linear IgG. | |||
*[[Membranous glomerulonephritis]] - IgG, C3, kappa, lambda. | |||
Notes: | |||
*Nonspecific linear IgG staining may be seen in [[diabetic nephropathy]]. | |||
===Immune complex-related disease=== | ===Immune complex-related disease=== | ||
| Line 191: | Line 213: | ||
Note: | Note: | ||
*Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only | *Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only the afferent. | ||
===Mesangial hypercellularity=== | ===Mesangial hypercellularity=== | ||
DDx: | DDx: | ||