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Difference between revisions of "Medical kidney diseases"
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→Pathologic DDx: more
m (→Immune complex-related disease: clarify) |
(→Pathologic DDx: more) |
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===Nephritic=== | ===Nephritic=== | ||
*Post-infectious glomerulonephritis | *Post-infectious glomerulonephritis. | ||
**Classically streptococcal | **Classically streptococcal. | ||
*Crescentic glomerulonephritis (AKA rapidly progressive glomerulonephritis (RPGN)) | *Crescentic glomerulonephritis (AKA rapidly progressive glomerulonephritis (RPGN)). | ||
**Anti-GBM disease | **Anti-GBM disease. | ||
**ANCA disease (e.g. Wegener's granulomatosis) | **ANCA disease (e.g. Wegener's granulomatosis). | ||
**Goodpasture's syndrome. | **Goodpasture's syndrome. | ||
===Nephrotic=== | ===Nephrotic=== | ||
*Minimal segmental disease (MSD) - AKA ''minimal change disease'' (MCD) | *Minimal segmental disease (MSD) - AKA ''minimal change disease'' (MCD). | ||
*Focal segmental glomerulosclerosis (FSGS) | *Focal segmental glomerulosclerosis (FSGS). | ||
*Membranous nephropathy. | *Membranous nephropathy. | ||
===Mixed presentation=== | ===Mixed presentation=== | ||
*IgA nephropathy, | *IgA nephropathy, | ||
*Focal proliferative glomerulosclerosis (FPGS) | *Focal proliferative glomerulosclerosis (FPGS). | ||
*Membranoproliferative glomerulonephritis (MPGN). | *Membranoproliferative glomerulonephritis (MPGN). | ||
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|IgA nephropathy | |IgA nephropathy | ||
| +ve IF for IgA | | +ve IF for IgA | ||
| | | +/-mesangial hypercellularity (???) | ||
| | | IgA +ve | ||
| mixed nephrotic/nephritic | | mixed nephrotic/nephritic | ||
| Clinical? | | Clinical? | ||
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| Image? | | Image? | ||
|- | |- | ||
|Membranoproliferative GN | |Membranoproliferative GN (MPGN) | ||
| | | thick GBM | ||
| Other findings? | | Other findings? | ||
| | | subepithelial deposits | ||
| mixed nephrotic/nephritic | | mixed nephrotic/nephritic | ||
| Clinical? | | Clinical? | ||
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|- | |- | ||
|Focal proliferative<br> glomerosclerosis (FPFS) | |Focal proliferative<br> glomerosclerosis (FPFS) | ||
| | | <50% of glomeruli partially sclerosis | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||
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|- | |- | ||
|Rapidly progressive GN (RPGN) | |Rapidly progressive GN (RPGN) | ||
| | | cresents | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||