Difference between revisions of "Medical kidney diseases"

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(→‎Nephrotic syndrome: +link to main)
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| focal sclerosis of gloms
| focal sclerosis of gloms
| +/-interstitial fibrosis
| +/-interstitial fibrosis
| EM?
| IF: negative; EM: foot process loss
| nephrotic syndrome
| nephrotic syndrome
| primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]]); unresponsive to steroids, worse prognosis than MCD
| primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]]); unresponsive to steroids, worse prognosis than MCD
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| Gloms with wire loops
| Gloms with wire loops
| mesangial hypercellularity
| mesangial hypercellularity
| EM?
| IF: diffuse granular capillary loop IgG, C3, kappa, lambda; EM diffuse subepithelial deposits - spike forming
| nephrotic syndrome
| nephrotic syndrome
| [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic
| [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic
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|-
|-
|[[Minimal change disease]] (MCD)
|[[Minimal change disease]] (MCD)
| EM changes
| foot process loss on [[EM]]
| usu. none
| usu. none
| EM changes
| EM: foot process loss
| nephrotic syndrome
| nephrotic syndrome
| primary vs. secondary ([[lymphoproliferative disorder]], NSAIDs); idiopathic responds to steroids
| primary vs. secondary ([[lymphoproliferative disorder]], NSAIDs); idiopathic responds to steroids
48,466

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