Difference between revisions of "Medical kidney diseases"

Medical kidney diseases (view source)

1,316 bytes added , 19:59, 13 November 2011

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 =Rare diseases=
+==Goodpasture syndrome==
+===General===
+*Very rare - estimated incidence 1/1-2 million.
+*Renal failure and pulmonary hemorrhage.<ref>{{cite journal | author=Goodpasture EW | title=The significance of certain pulmonary lesions in relation to the etiology of influenza | journal=Am J Med Sci | year=1919 | volume=158 | pages=863–870 | doi=10.1097/00000441-191911000-00012 | issue=6}}</ref>
+Clinical DDx:
+*[[Wegener granulomatosis]].
+*Azathioprine toxicity.<ref>{{Cite journal  | last1 = Stetter | first1 = M. | last2 = Schmidl | first2 = M. | last3 = Krapf | first3 = R. | title = Azathioprine hypersensitivity mimicking Goodpasture's syndrome. | journal = Am J Kidney Dis | volume = 23 | issue = 6 | pages = 874-7 | month = Jun | year = 1994 | doi =  | PMID = 8203372 }}</ref>
+Tx:
+*Immune suppression & plasma exchange.<ref name=pmid12597309>{{Cite journal  | last1 = Shah | first1 = MK. | last2 = Hugghins | first2 = SY. | title = Characteristics and outcomes of patients with Goodpasture's syndrome. | journal = South Med J | volume = 95 | issue = 12 | pages = 1411-8 | month = Dec | year = 2002 | doi =  | PMID = 12597309 }}</ref>
+===Microscopic===
+Features:
+*RPGN.
+**Crescentic glomerulonephritis.
+===IF===
+*Linear IgG deposits.
+DDx:
+*AGBM disease.
+**Goodpasture syndrome without the pulmonary hemorrhage.
 ==Thin glomerular basement membrane disease==
 ===General===