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*Assoc. with colonic diverticula, aortic aneurysm, mitral valve prolapse. | *Assoc. with colonic diverticula, aortic aneurysm, mitral valve prolapse. | ||
====Liver and PKD==== | ====Liver cysts and PKD==== | ||
=====General===== | |||
Features: | |||
*Most common extra-renal manifestation of PKD; dependent on age, sex and renal function:<ref name=pmid9186898>{{cite journal |author=Perrone RD |title=Extrarenal manifestations of ADPKD |journal=Kidney Int. |volume=51 |issue=6 |pages=2022–36 |year=1997 |month=June |pmid=9186898 |doi= |url=http://www.nature.com/ki/journal/v51/n6/pdf/ki1997276a.pdf}}</ref> | |||
**Age dependence: | |||
***10-17% <40 years old have liver cysts. | |||
***70-75% >60 years old have liver cysts. | |||
**Renal function: | |||
***60-70% of patient with ESRD and near-ESRD. | |||
**Females more often affected. | |||
*Hepatic function usu. perserved. | |||
Complications:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref> | Complications:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref> | ||
#Infected cyst. | #Infected cyst. | ||
#Cholangiocarcinoma. | #Cholangiocarcinoma. | ||
=====Microscopic===== | |||
* | Features: | ||
*''Von Meyenburg complexes'': | |||
**Cluster of dilated ducts with "altered" bile. | |||
**Surrounded by collagenous stroma. | |||
See also: ''[[Medical liver disease]]''. | See also: ''[[Medical liver disease]]''. |
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