Difference between revisions of "Medical kidney diseases"

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*Assoc. with colonic diverticula, aortic aneurysm, mitral valve prolapse.
*Assoc. with colonic diverticula, aortic aneurysm, mitral valve prolapse.


====Liver and PKD====
====Liver cysts and PKD====
=====General=====
Features:
*Most common extra-renal manifestation of PKD; dependent on age, sex and renal function:<ref name=pmid9186898>{{cite journal |author=Perrone RD |title=Extrarenal manifestations of ADPKD |journal=Kidney Int. |volume=51 |issue=6 |pages=2022–36 |year=1997 |month=June |pmid=9186898 |doi= |url=http://www.nature.com/ki/journal/v51/n6/pdf/ki1997276a.pdf}}</ref>
**Age dependence:
***10-17% <40 years old have liver cysts.
***70-75% >60 years old have liver cysts.
**Renal function:
***60-70% of patient with ESRD and near-ESRD.
**Females more often affected.
*Hepatic function usu. perserved.
 
Complications:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref>
Complications:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref>
#Infected cyst.
#Infected cyst.
#Cholangiocarcinoma.
#Cholangiocarcinoma.


Cysts:
=====Microscopic=====
*Cysts in the liver, like the kidney, are thought to enlarge with age.
Features:
*''Von Meyenburg complexes'':
**Cluster of dilated ducts with "altered" bile.
**Surrounded by collagenous stroma.
 


''Von Meyenburg complexes'':
*Cluster of dilated ducts with "altered" bile.
*Surrounded by collagenous stroma.


See also: ''[[Medical liver disease]]''.
See also: ''[[Medical liver disease]]''.
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