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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 20:31, 21 October 2010
, 20:31, 21 October 2010→Microscopic: +more
(→Diabetes mellitus: +armani-ebstein) |
(→Microscopic: +more) |
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Features:<ref name=pmid19825147>{{cite journal |author=Zelmanovitz T, Gerchman F, Balthazar AP, Thomazelli FC, Matos JD, Canani LH |title=Diabetic nephropathy |journal=Diabetol Metab Syndr |volume=1 |issue=1 |pages=10 |year=2009 |pmid=19825147 |pmc=2761852 |doi=10.1186/1758-5996-1-10 |url=}}</ref> | Features:<ref name=pmid19825147>{{cite journal |author=Zelmanovitz T, Gerchman F, Balthazar AP, Thomazelli FC, Matos JD, Canani LH |title=Diabetic nephropathy |journal=Diabetol Metab Syndr |volume=1 |issue=1 |pages=10 |year=2009 |pmid=19825147 |pmc=2761852 |doi=10.1186/1758-5996-1-10 |url=}}</ref> | ||
*Thick glomerular basement membrane (GBM). | *Thick glomerular basement membrane (GBM). | ||
* | *Thickened (eosinophilic) tunica media in both the afferent and efferent arterioles.<ref name=pmid12032631>{{cite journal |author=Østerby R, Hartmann A, Bangstad HJ |title=Structural changes in renal arterioles in Type I diabetic patients |journal=Diabetologia |volume=45 |issue=4 |pages=542–9 |year=2002 |month=April |pmid=12032631 |doi=10.1007/s00125-002-0780-2 |url=}}</ref> | ||
*Mesangial matrix expansion - leads to nodule formation ''Kimmelstiel-Wilson nodules'' (''nodular glomerulosclerosis''). | *Mesangial matrix expansion - leads to nodule formation ''Kimmelstiel-Wilson nodules'' (''nodular glomerulosclerosis''). | ||
Other: | |||
*Armanni-Ebstein change - cytoplasmic vacuolization of tubular cells (usu. loop of Henle) -- innermost cortex, outer medulla;<ref name=pmid13478656>{{cite journal |author=RITCHIE S, WAUGH D |title=The pathology of Armanni-Ebstein diabetic nephropathy |journal=Am. J. Pathol. |volume=33 |issue=6 |pages=1035–57 |year=1957 |pmid=13478656 |pmc=1934668 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934668/?page=1}}</ref> not specific to diabetes mellitus.<ref name=pmid20875709>{{cite journal |author=Zhou C, Byard RW |title=Armanni-Ebstein phenomenon and hypothermia |journal=Forensic Sci Int |volume= |issue= |pages= |year=2010 |month=September |pmid=20875709 |doi=10.1016/j.forsciint.2010.08.018 |url=}}</ref> | |||
Other - with weak evidence: | Other - with weak evidence: | ||
*Extra efferent vessels.<ref name=pmid17490718>{{cite journal |author=Stout LC, Whorton EB |title=Pathogenesis of extra efferent vessel development in diabetic glomeruli |journal=Hum. Pathol. |volume=38 |issue=8 |pages=1167–77 |year=2007 |month=August |pmid=17490718 |doi=10.1016/j.humpath.2007.01.019 |url=}}</ref> | *Extra efferent vessels.<ref name=pmid17490718>{{cite journal |author=Stout LC, Whorton EB |title=Pathogenesis of extra efferent vessel development in diabetic glomeruli |journal=Hum. Pathol. |volume=38 |issue=8 |pages=1167–77 |year=2007 |month=August |pmid=17490718 |doi=10.1016/j.humpath.2007.01.019 |url=}}</ref> | ||
Memory device: | Memory device: | ||
*GBM = ''thick '''G'''BM'', '''''b'''oth afferent & efferent artiole thickened'', '''''m'''esangial matrix expansion''. | *GBM = ''thick '''G'''BM'', '''''b'''oth afferent & efferent artiole thickened'', '''''m'''esangial matrix expansion''. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Nodular_glomerulosclerosis.jpeg Nodular glomerulosclerosis (WC)]. | |||
*[http://www.markwickmd.com/images/pages/armani_ebstein_lesion.jpg Armanni-Ebstein lesion (markwickmd.com)]. | |||
Notes: | Notes: | ||