Difference between revisions of "Malignant melanoma"

Malignant melanoma (view source)

81 bytes added , 09:55, 3 July 2013

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 #*Positive margin = melanoma cell is touching ink.
 #*Very close is reported as "clearance < 0.1 mm".
-#Use [[immunostain]]s to assist the assessment of difficult cases:<ref name=pmid21797920>{{Cite journal  | last1 = Kim | first1 = J. | last2 = Taube | first2 = JM. | last3 = McCalmont | first3 = TH. | last4 = Glusac | first4 = EJ. | title = Quantitative comparison of MiTF, Melan-A, HMB-45 and Mel-5 in solar lentigines and melanoma in situ. | journal = J Cutan Pathol | volume = 38 | issue = 10 | pages = 775-9 | month = Oct | year = 2011 | doi = 10.1111/j.1600-0560.2011.01763.x | PMID = 21797920 }}</ref>
+#Use [[immunostain]]s to assist the assessment of difficult cases:
 #*MiTF is considered the preferred marker.
-#*MART-1 (Melan A) is considered to overestimate melanocytes; it should ''not'' be used.
+#*MART-1 (Melan A) is considered to overestimate melanocytes; it should ''not'' be used.<ref name=pmid21797920>{{Cite journal  | last1 = Kim | first1 = J. | last2 = Taube | first2 = JM. | last3 = McCalmont | first3 = TH. | last4 = Glusac | first4 = EJ. | title = Quantitative comparison of MiTF, Melan-A, HMB-45 and Mel-5 in solar lentigines and melanoma in situ. | journal = J Cutan Pathol | volume = 38 | issue = 10 | pages = 775-9 | month = Oct | year = 2011 | doi = 10.1111/j.1600-0560.2011.01763.x | PMID = 21797920 }}</ref>
+#*S-100 also marks follicular dendritic cells; it is ''not'' a preferred marker.
 ====Subtypes====