Difference between revisions of "Malignant melanoma"

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(→‎Skin: more)
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===Skin===
===Skin===
Features (skin):
Features (skin):
*Architecture:  
#Architecture:  
**Sheeting - diagnostic.
#*Sheeting - diagnostic.
**Asymmetry.  
#*Asymmetry.  
*Lack of maturation.
#Lack of maturation.
*+/-[[Nuclear atypia]].
#+/-[[Nuclear atypia]].
**May be seen in [[Spitz nevus]].
#*May be seen in a [[Spitz nevus]].
*+/-Upward scatter of melanocytes [[AKA]] intraepidermal ascent - "cannonball" appearance.
#+/-Upward scatter of melanocytes [[AKA]] intraepidermal ascent - "cannonball" appearance.
**No diagnostic significance in the following cases:
#*No diagnostic significance in the following cases:
***Acral sites - see: ''[[Acral nevus]]''.
#**Acral sites - see: ''[[Acral nevus]]''.
***Histologic evidence of trauma.
#**Histologic evidence of trauma.
****Thick dense ''stratum corneum''.  
#***Thick dense ''stratum corneum''.  


Maturation - with depth:
Maturation - with depth:
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