Difference between revisions of "Malignant melanoma"

Malignant melanoma (view source)

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 =====Tumour stage=====
 Melanoma staging is based primarily on the Breslow thickness:<ref>{{Cite journal  | last1 = Nowecki | first1 = ZI. | last2 = Rutkowski | first2 = P. | last3 = Michej | first3 = W. | title = The survival benefit to patients with positive sentinel node melanoma after completion lymph node dissection may be limited to the subgroup with a primary lesion Breslow thickness greater than 1.0 and less than or equal to 4 mm (pT2-pT3). | journal = Ann Surg Oncol | volume = 15 | issue = 8 | pages = 2223-34 | month = Aug | year = 2008 | doi = 10.1245/s10434-008-9965-3 | PMID = 18506535 }}</ref><ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2013/SkinMelanoma_13protocol_3300.doc http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2013/SkinMelanoma_13protocol_3300.doc]. Accessed on: 2 January 2014.</ref>
-*pT1 <= 1.0 mm.
+*pT1 ≤ 1.0 mm.
-**pT1a: no ulceration, <1 mitoses/mm<sup>2</sup>.
+**pT1a: ≤ 0.8 mm, no ulceration.
-**pT1b: ulceration present ''or'' >=1 mitoses/mm<sup>2</sup>.
+**pT1b: ulceration present ''or'' 0.8 mm  < thickness ≤ 1.0 mm (with or without ulceration).
 *pT2 1.01 mm to 2.0 mm.
 **pT2a: no ulceration.