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Difference between revisions of "Lymphoma"
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→IHC
m (→B cell markers) |
(→IHC) |
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*CD43 -- +ve in mantle cell lymphoma | *CD43 -- +ve in mantle cell lymphoma | ||
* | *ALK1<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/601284 http://www.ncbi.nlm.nih.gov/omim/601284]. Accessed on: 31 August 2010.</ref> - prognostic in anaplastic large cell lymphoma (ALCL).<ref name=pmid9250148>{{cite journal |author=Pittaluga S, Wlodarska I, Pulford K, ''et al.'' |title=The monoclonal antibody ALK1 identifies a distinct morphological subtype of anaplastic large cell lymphoma associated with 2p23/ALK rearrangements |journal=Am. J. Pathol. |volume=151 |issue=2 |pages=343–51 |year=1997 |month=August |pmid=9250148 |pmc=1858018 |doi= |url=}}</ref> | ||
*TIA1.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/603518 http://www.ncbi.nlm.nih.gov/omim/603518]. Accessed on: 18 August 2010.</ref> | *TIA1 - cytotoxic T-cell.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/603518 http://www.ncbi.nlm.nih.gov/omim/603518]. Accessed on: 18 August 2010.</ref> | ||
*Granzyme B. | *Granzyme B. | ||
====B cell markers==== | ====B cell markers==== | ||
| Line 103: | Line 103: | ||
*BCL6 -- follicle center. | *BCL6 -- follicle center. | ||
*BCL2 -- normally negative in germinal centers (GCs), marks T cell; +ve in small B cell lymphomas. | *BCL2 -- normally negative in germinal centers (GCs), marks T cell; +ve in small B cell lymphomas. | ||
*MUM1. | *MUM1 -- -ve in follicular lymphoma, +ve in DLBCL that did not arise from follicular lymphoma. | ||
====Follicular dendritic cells==== | ====Follicular dendritic cells==== | ||