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Difference between revisions of "Lymphoma"
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+PMBL
(→B cell lymphomas: +HCL) |
(+PMBL) |
||
| Line 276: | Line 276: | ||
*CD20 +ve. | *CD20 +ve. | ||
*TIA-1 -ve. | *TIA-1 -ve. | ||
==Primary mediastinal B-cell lymphoma== | |||
*Abbreviated ''PMBL''. | |||
*[[AKA]] ''primary mediastinal large B-cell lymphoma''. | |||
===General=== | |||
Features:<ref name=pmid19074109 >{{Cite journal | last1 = Johnson | first1 = PW. | last2 = Davies | first2 = AJ. | title = Primary mediastinal B-cell lymphoma. | journal = Hematology Am Soc Hematol Educ Program | volume = | issue = | pages = 349-58 | month = | year = 2008 | doi = 10.1182/asheducation-2008.1.349 | PMID = 19074109 }}</ref><ref name=pmid20207294>{{Cite journal | last1 = Coso | first1 = D. | last2 = Rey | first2 = J. | last3 = Bouabdallah | first3 = R. | title = [Primary mediastinal B-cell lymphoma] | journal = Rev Pneumol Clin | volume = 66 | issue = 1 | pages = 32-5 | month = Feb | year = 2010 | doi = 10.1016/j.pneumo.2009.12.007 | PMID = 20207294 }}</ref> | |||
*Rare. | |||
*Young adults. | |||
===Microscopic=== | |||
Features: | |||
*Similar to DLBCL. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Primary_mediastinal_large_B-cell_lymphoma_-_very_high_mag.jpg PMBL - very high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Primary_mediastinal_large_B-cell_lymphoma_-_intermed_mag.jpg PMBL - intermed. mag. (WC)]. | |||
==Anaplastic large cell lymphoma== | ==Anaplastic large cell lymphoma== | ||
| Line 401: | Line 418: | ||
| very common | | very common | ||
| Burkitt lymphoma, ALCL, Hodgkin lymphoma | | Burkitt lymphoma, ALCL, Hodgkin lymphoma | ||
|- | |||
| Primary mediastinal B-cell lymphoma | |||
| large (>2x RBC, often larger), variable size | |||
| mediastinum | |||
| histomorphology ? | |||
| IHC ? | |||
| translocations ? | |||
| predominantly young adults, better prognosis than DLBCL | |||
| uncommon | |||
| DLBCL | |||
|- <!-- | |- <!-- | ||
| Name | | Name | ||