Difference between revisions of "Lymph node pathology"

Lymph node pathology (view source)

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 {{Main|Progressive transformation of germinal centers}}
 *Abbreviated as ''PTGC''.
-===Microscopic===
-Features:
-*Follicular hyperplasia (many follicles).
-*'''Focally''' large germinal centers with:
-**Poorly demarcated germinal center (GC)/mantle zone interfaces (as GCs infiltrated by mantle zone lymphocytes) -- '''key feature'''.<ref name=pmid12145465>{{cite journal |author=Verma A, Stock W, Norohna S, Shah R, Bradlow B, Platanias LC |title=Progressive transformation of germinal centers. Report of 2 cases and review of the literature |journal=Acta Haematol. |volume=108 |issue=1 |pages=33–8 |year=2002 |pmid=12145465 |doi= |url=}}</ref>
-**Expanded mantle zone.
-Images:
-*[http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_very_low_mag.jpg PTGCs - very low mag. (WC)].
-*[http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_low_mag.jpg PTGCs - low mag. (WC)].
 ==Reactive follicular hyperplasia==