Difference between revisions of "Lymph node pathology"

Lymph node pathology (view source)

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 ==Kimura lymphadenopathy==
-===General===
+{{Main|Kimura disease}}
-*[[AKA]] ''eosinophilic lymphogranuloma'', ''Kimura disease''.
-*Chronic inflammatory disorder - suspected to be infectious.
-Clinical:
-*Usually neck, periauricular.
-*Peripheral blood eosinophilia.
-*Increased blood IgE.
-===Epidemiology===
-*Males > females.
-*Young.
-*Asian.
 ===Microscopic===
-Features:<ref name=Ref_ILNP190>{{Ref ILNP|190}}</ref>
+Features:
-*Angiolymphoid proliferation.
+*Abundant eosinophils.
-**Thick walled blood vessels with (plump) hobnail endothelial cells.<ref>URL: [http://emedicine.medscape.com/article/1098777-diagnosis http://emedicine.medscape.com/article/1098777-diagnosis]. Accessed on: 8 August 2010.</ref>
+*Thick-wall blood vessels.
-*Eosinophils - abundant - '''key feature'''.
-Notes:
-*Abundant eosinophils: consider Langerhans cell histiocytosis.
-Images:
-*[http://commons.wikimedia.org/wiki/File:Kimura_disease_-_very_high_mag.jpg Kimura disease - very high mag. (WC)].
-*[http://commons.wikimedia.org/wiki/File:Kimura_disease_-_high_mag.jpg Kimura disease - high mag. (WC)].
-*[http://commons.wikimedia.org/wiki/File:Kimura_disease_-_intermed_mag.jpg Kimura disease - intermed. mag. (WC)].
-===IHC===
-*Used to rule-out a clonal population.
 ==Rosai-Dorfman disease==