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Difference between revisions of "Lymph node pathology"
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→Overview in a table
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| dependent on tumour type (see ''[[IHC]]'') | | dependent on tumour type (see ''[[IHC]]'') | ||
| dependent on morphology, [[endometriosis]] (mimics adenocarcinoma), ectopic decidua (mimics [[SCC]]) | | dependent on morphology, [[endometriosis]] (mimics adenocarcinoma), ectopic decidua (mimics [[SCC]]) | ||
| | | [[Image:Crc_met_to_node1.jpg|thumb|center|125px| CRC metastasis]] [[Image:Breast_carcinoma_in_a_lymph_node.jpg|thumb|center|125px | Breast metastasis]] | ||
Image:Breast_carcinoma_in_a_lymph_node.jpg | Breast metastasis | |||
|- | |- | ||
| [[Progressive transformation of germinal centers]] | | [[Progressive transformation of germinal centers]] | ||
| Line 46: | Line 44: | ||
| IHC to r/o ''nodular lymphocyte predominant [[Hodgkin lymphoma]]'' (NLPHL) | | IHC to r/o ''nodular lymphocyte predominant [[Hodgkin lymphoma]]'' (NLPHL) | ||
| NLPHL, follicular hyperplasia | | NLPHL, follicular hyperplasia | ||
| | | [[Image:Progressive transformation_of_germinal_centres_-1-_very_low_mag.jpg|thumb|center|150px | PTGC - very low mag.]] | ||
|- | |- | ||
| [[Toxoplasmosis]] | | [[Toxoplasmosis]] | ||
| Line 53: | Line 51: | ||
| IHC for toxoplasma | | IHC for toxoplasma | ||
| NSRFH, HIV/AIDS, [[Hodgkin's lymphoma]] | | NSRFH, HIV/AIDS, [[Hodgkin's lymphoma]] | ||
| | | [[Image:Toxoplasmosis_lymphadenopathy_-_low_mag.jpg|thumb|center|150px | TL - low mag.]] | ||
|- | |- | ||
| [[Kikuchi disease]] (histiocystic necrotizing lymphadenitis) | | [[Kikuchi disease]] (histiocystic necrotizing lymphadenitis) | ||
| Line 60: | Line 58: | ||
| IHC for large cell lymphoma (CD30 + others) | | IHC for large cell lymphoma (CD30 + others) | ||
| [[SLE]] (has (blue) hematoxylin bodies in necrotic areas), large cell lymphomas | | [[SLE]] (has (blue) hematoxylin bodies in necrotic areas), large cell lymphomas | ||
| | | [[Image:Histiocytic_necrotizing_lymphadenitis_-_very_high_mag.jpg |thumb|center|150px| HNL - very high mag.]] | ||
|- | |- | ||
| [[Cat-scratch disease]] | | [[Cat-scratch disease]] | ||
| Line 67: | Line 65: | ||
| B. henselae, [[Dieterle stain]] | | B. henselae, [[Dieterle stain]] | ||
| [[HIV]]/AIDS, NSRFH | | [[HIV]]/AIDS, NSRFH | ||
| [ | | [[Image:Cat_scratch_disease_-_very_low_mag.jpg|thumb|center|150px|Cat scratch - very low mag.]] | ||
|- | |- | ||
| [[Dermatopathic lymphadenopathy]] | | [[Dermatopathic lymphadenopathy]] | ||
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| S100+ve (interdigitating dendritic cells), CD1a+ve (Langerhans cells) | | S100+ve (interdigitating dendritic cells), CD1a+ve (Langerhans cells) | ||
| [[cutaneous T-cell lymphoma]] | | [[cutaneous T-cell lymphoma]] | ||
| [ | | [[Image:Dermatopathic_lymphadenopathy_-_intermed_mag.jpg |thumb|center|150px| DL - intermed. mag.]] | ||
|- | |- | ||
| [[Kimura disease]] | | [[Kimura disease]] | ||
| Line 81: | Line 79: | ||
| IHC ? | | IHC ? | ||
| [[Langerhans cell histiocytosis]], drug reaction, [[angiolymphoid hyperplasia with eosinophilia]] | | [[Langerhans cell histiocytosis]], drug reaction, [[angiolymphoid hyperplasia with eosinophilia]] | ||
| [ | | [[Image:Kimura_disease_-_very_high_mag.jpg|thumb|center|150px|Kimura disease - very high mag.]] | ||
|- | |- | ||
| [[Langerhans cell histiocytosis]] | | [[Langerhans cell histiocytosis]] | ||
| Line 88: | Line 86: | ||
| S100+, CD1a+ | | S100+, CD1a+ | ||
| [[Kimura disease]] (eosinophilia), [[Rosai-Dorfman disease]] | | [[Kimura disease]] (eosinophilia), [[Rosai-Dorfman disease]] | ||
| | | [[Image:Langerhans_cell_histiocytosis_-_very_high_mag.jpg|thumb|center|150px|LCH - very high mag.]] | ||
|- | |- | ||
| [[Rosai-Dorfman disease]] | | [[Rosai-Dorfman disease]] | ||
| Line 95: | Line 93: | ||
| S100+, CD1a- | | S100+, CD1a- | ||
| Langerhans cell histiocytosis | | Langerhans cell histiocytosis | ||
| | | [[Image:Emperipolesis_-_very_high_mag.jpg |thumb|center|150px | RDD - very high mag.]] | ||
|- | |- | ||
| [[Systemic lupus erythematosus]] lymphadenopathy | | [[Systemic lupus erythematosus]] lymphadenopathy | ||
| Line 102: | Line 100: | ||
| IHC for large cell lymphoma (CD30 + others) | | IHC for large cell lymphoma (CD30 + others) | ||
| [[Kikuchi disease]], large cell [[lymphoma]]s | | [[Kikuchi disease]], large cell [[lymphoma]]s | ||
| | | [[Image:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg|thumb|center|150px | SLEL - high mag.]] | ||
|- | |- | ||
| [[Castleman disease]], hyaline vascular variant | | [[Castleman disease]], hyaline vascular variant | ||
| Line 109: | Line 107: | ||
| IHC - to r/o [[mantle cell lymphoma]] | | IHC - to r/o [[mantle cell lymphoma]] | ||
| mantle cell lymphoma, [[HIV]]/AIDS | | mantle cell lymphoma, [[HIV]]/AIDS | ||
| | | [[Image:Castleman_disease_-_intermed_mag.jpg|thumb|center|150px | CD - intermed. mag.]] | ||
|- | |- | ||
| Castleman disease, plasma cell variant | | Castleman disease, plasma cell variant | ||
| Line 123: | Line 121: | ||
| SMA+, cyclin D1+ | | SMA+, cyclin D1+ | ||
| [[schwannoma]] | | [[schwannoma]] | ||
| [ | | [[Image:Intranodal_palisaded_myofibroblastoma_-_very_high_mag.jpg|thumb|center|150px|IPM - very high mag.]] | ||
|- | |- | ||
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