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Difference between revisions of "Lymph node pathology"
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→Castleman disease
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===Microscopic=== | ===Microscopic=== | ||
Hyaline-vascular variant - features:<ref>URL: [http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/a_rare_case_of_castleman_s_disease_presenting_as_cervical_neck_mass.html http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/a_rare_case_of_castleman_s_disease_presenting_as_cervical_neck_mass.html]. Accessed on: 15 June 2010.</ref><ref name=Ref_ILNP236>{{Ref ILNP|236}}</ref> | |||
*Pale concentric (expanded) mantle zone lymphocytes. | *Pale concentric (expanded) mantle zone lymphocytes - '''key feature'''. | ||
**"Regressed | **"Regressed follicles" - germinal center (pale area) is small. | ||
*"Lollipops" | *"Lollipops": | ||
**Germinal centers fed by prominent (radially penetrating sclerotic) vessels; lollipop-like appearance. | |||
*Two germinal centers in one follicle. | *Two germinal centers in one follicle. | ||
*Hyaline material (pink acellular stuff on H&E) in germinal center. | |||
*Sinuses effaced (lost). | |||
*Mitoses absent. | |||
Plasma cell variant - features:<ref name=Ref_ILNP236>{{Ref ILNP|236}}</ref> | |||
*Interfollicular sheets of plasma cells - '''key feature'''. | |||
*Active germinal centers - mitoses present. | |||
*Sinus perserved. | |||
==Cat-scratch disease== | ==Cat-scratch disease== | ||