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Difference between revisions of "Lymph node pathology"
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Image: [http://pleiad.umdnj.edu/hemepath/normal_node/normal_node.html Normal lymph node (umdnj.edu)]. | Image: [http://pleiad.umdnj.edu/hemepath/normal_node/normal_node.html Normal lymph node (umdnj.edu)]. | ||
==Diffuse | ==Diffuse paracortical hyperplasia== | ||
===General=== | ===General=== | ||
*Benign. | *Benign. | ||
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*[http://www.webpathology.com/image.asp?case=386&n=1 Cat-scratch disease (webpathology.com)]. | *[http://www.webpathology.com/image.asp?case=386&n=1 Cat-scratch disease (webpathology.com)]. | ||
*[http://www.webpathology.com/image.asp?n=2&Case=386 Cat-scratch disease - high mag. (webpathology.com)] | *[http://www.webpathology.com/image.asp?n=2&Case=386 Cat-scratch disease - high mag. (webpathology.com)] | ||
==Toxoplasma lymphadenitis== | |||
===General=== | |||
*Caused by protozoan ''Toxoplasma gondii''. | |||
===Microscopic=== | |||
Features:<ref name=Ref_ILNP113>{{Ref ILNP|113}}</ref> | |||
*Reactive germinal centers (pale areas - larger than usual). | |||
*Epithelioid cells - perifollicular & intrafollicular. | |||
**Loose aggregates of histiocytes (do not form round granulomas): | |||
***Abundant pale cytoplasm. | |||
***Nucleoli. | |||
*Monocytoid cells (monocyte-like cells) - in cortex & paracortex. | |||
**Large cells in islands/sheets '''key feature''' with: | |||
***Abundant pale cytoplasm - '''important'''. | |||
***Well-defined cell border - '''important'''. | |||
***Singular nucleus. | |||
Notes: | |||
*Monocytoid cells CD68 -ve. | |||
==Dermatopathic lymphadenopathy== | ==Dermatopathic lymphadenopathy== | ||