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Difference between revisions of "Lung metastasis"
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→Microscopic: +ddx
(→Gross) |
(→Microscopic: +ddx) |
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Features: | Features: | ||
*Variable - dependent on site of origin. | *Variable - dependent on site of origin. | ||
*[[Colorectal adenocarcinoma]] - usually distinctive morphologically: | |||
**Typically gland forming. | |||
***Ellipsoid/elongated pseudostratified nuclei with moderate [[nuclear atypia]]. | |||
***+/-Dirty necrosis. | |||
*Others: | |||
**[[Urothelial carcinoma]] - may mimic [[squamous cell carcinoma of the lung]]. | |||
**Upper GI adenocarcinoma (e.g. [[gastric adenocarcinoma]]) - may mimic [[lung adenocarcinoma]]. | |||
**Breast carcinoma - esp. [[ductal carcinoma of the breast]] - may mimic [[lung adenocarcinoma]]. | |||
DDx: | |||
* | *[[Pulmonary meningothelial-like nodule]].<ref name=pmid23109985>{{Cite journal | last1 = Kfoury | first1 = H. | last2 = Arafah | first2 = MA. | last3 = Arafah | first3 = MM. | last4 = Alnassar | first4 = S. | last5 = Hajjar | first5 = W. | title = Mimicry of Minute Pulmonary Meningothelial-like Nodules to Metastatic Deposits in a Patient with Infiltrating Lobular Carcinoma: A Case Report and Review of the Literature. | journal = Korean J Pathol | volume = 46 | issue = 1 | pages = 87-91 | month = Feb | year = 2012 | doi = 10.4132/KoreanJPathol.2012.46.1.87 | PMID = 23109985 }}</ref> | ||
*[[Carcinoid tumourlet]]. | |||
*[[Carcinoid lung tumour]]. | |||
* | |||
* | |||
===Images=== | ===Images=== | ||
| Line 67: | Line 70: | ||
Image:Metastatic prostatic adenocarcinoma (5918338484).jpg | Prostate carcinoma. (WC/Rosen) | Image:Metastatic prostatic adenocarcinoma (5918338484).jpg | Prostate carcinoma. (WC/Rosen) | ||
</gallery> | </gallery> | ||
==IHC== | ==IHC== | ||
*TTF-1 -ve/+ve. | *TTF-1 -ve/+ve. | ||