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The '''long power list''' is a collection of diagnoses based on site and pathologic characteristics. | The '''long power list''' is a collection of diagnoses based on site and pathologic characteristics. It builds on the ''[[short power list]]''. | ||
=Site= | |||
==Bone & cartilage== | |||
===General=== | |||
Benign - bone: | |||
*[[Aneurysmal bone cyst]]. | |||
*[[Brown tumour]]. | |||
*[[Paget's disease of bone]]. | |||
*[[Osteomyelitis]]. | |||
*[[Fibrous dysplasia]]. | |||
Benign - bone tumours: | |||
*[[Osteoid osteoma]]. | |||
*[[Osteoblastoma]]. | |||
*[[Osteochondroma]]. | |||
*[[Adamantinoma]]. | |||
Benign - cartilage: | |||
*[[Chondroma]]. | |||
*[[Enchondroma]]. | |||
*[[Chondroblastoma]]. | |||
Malignant - bone: | |||
*[[Fracture of bone due to metastatic carcinoma|Metastatic carcinoma]]. | |||
*[[Plasma cell neoplasm]]. | |||
*[[Osteosarcoma]]. | |||
*[[Ewing sarcoma]]. | |||
*[[Giant cell tumour of bone]]. | |||
Malignant - cartilage: | |||
*[[Chondrosarcoma]]. | |||
Unusual genetic conditions: | |||
*[[Langerhans cell histiocytosis]]. | |||
*[[Gaucher disease]]. | |||
===Femoral head=== | |||
Benign: | |||
*[[Osteoarthritis]]. | |||
*[[Avascular necrosis of the femoral head]]. | |||
*[[Rheumatoid arthritis]]. | |||
Uncommon - benign (fracture): | |||
*Trauma. | |||
*[[Osteoporosis]]. | |||
Uncommon - benign pediatric: | |||
*[[Slipped capital femoral epiphysis]] (SCFE). | |||
*[[Legg–Calvé–Perthes syndrome]]. | |||
Uncommon - malignant (fracture): | |||
*[[Metastasis]]. | |||
==Breast pathology== | |||
Benign - common: | |||
*Normal. | |||
*[[Fibrocystic change]]. | |||
*[[Apocrine metaplasia]]. | |||
*[[Columnar cell change]]. | |||
*[[Fibroadenoma]]. | |||
*[[Phyllodes tumour]]. | |||
*[[Intraductal papilloma of the breast]]. | |||
*[[Florid epithelial hyperplasia]]. | |||
*[[Sclerosing adenosis]]. | |||
Benign - uncommon: | |||
*[[Flat epithelial atypia]]. | |||
*[[Complex sclerosing lesion]]. | |||
*Breast abscess. | |||
*[[Fat_necrosis_of_the_breast|Breast with fat necrosis]]. | |||
*[[Microglandular adenosis]]. | |||
*[[Collagenous spherulosis]]. | |||
*[[Lactational change]]. | |||
*[[Diabetic mastopathy]]. | |||
Non-invasive: | |||
*[[ADH]]. | |||
*[[DCIS]]. | |||
**Subtypes: cribriform, solid, papillary, micropapillary. | |||
*[[ALH]]. | |||
*[[LCIS]]. | |||
Invasive - epithelial: | |||
*[[Invasive ductal carcinoma of the breast]]. | |||
*[[Invasive lobular carcinoma]]. | |||
*[[Papillary carcinoma of the breast]]. | |||
*[[Invasive micropapillary carcinoma of the breast]]. | |||
*[[Invasive cribriform carcinoma of the breast]]. | |||
*[[Tubular carcinoma of the breast]]. | |||
*[[Medullary breast carcinoma]]. | |||
*[[Mucinous breast carcinoma]]. | |||
*[[Metaplastic breast carcinoma]]. | |||
Invasive - non-epithelial: | |||
*[[Phyllodes tumour]]. | |||
*[[Angiosarcoma]]. | |||
Invasive - salivary gland-like: | |||
*[[Adenoid cystic carcinoma of the breast]]. | |||
*[[Carcinoma ex pleomorphic adenoma]] of the breast. | |||
==Cardiovascular pathology== | |||
===General=== | |||
*[[Thrombosis]] (embolism). | |||
*[[Vasculitis]]. | |||
**Large vessel: | |||
***[[Giant cell arteritis]]. | |||
***[[Takayasu arteritis]]. | |||
**Medium vessel: | |||
***[[Polyarteritis nodosa]]. | |||
***[[Kawasaki disease]]. | |||
**Small vessel: | |||
***[[Microscopic polyangiitis]]. | |||
***[[Granulomatosis with polyangiitis]] (Wegener's granulomatosis). | |||
***[[Eosinophilic granulomatosis with polyangiitis]] (Churg-Strauss syndrome). | |||
***[[Leukocytoclastic vasculitis]]. | |||
*[[Amyloid]] deposition. | |||
*[[Hyperplastic arteriolosclerosis]]. | |||
*[[Fibromuscular dysplasia]]. | |||
===Aorta=== | |||
*[[Atherosclerosis]]. | |||
*[[Aortic dissection]]. | |||
**[[Cystic medial degeneration]]. | |||
**Traumatic dissection - see ''[[blunt force injury]]''. | |||
*Mycotic aneurysm. | |||
===Cardiac valves=== | |||
*[[Infective endocarditis]]. | |||
*[[Myxomatous degeneration]]. | |||
*[[Papillary fibroelastoma]]. | |||
====Aortic valve==== | |||
*[[Calcific aortic stenosis]]. | |||
====Mitral valve==== | |||
*[[Rheumatic heart disease]]. | |||
====Tricuspid valve==== | |||
*[[Nonbacterial thrombotic endocarditis]] (NBTE). | |||
===Heart=== | |||
Common - benign: | |||
*[[Atrial myxoma]]. | |||
Uncommon - benign: | |||
*Lipoma. | |||
*[[Rhabdomyoma]]. | |||
Uncommon - malignant: | |||
*[[Pleomorphic undifferentiated sarcoma]]. | |||
*[[Angiosarcoma]]. | |||
==Dermatopathology== | |||
Benign - non-melanocytic: | |||
*[[Epidermal inclusion cyst]]. | |||
*[[Pilar cyst]]. | |||
*[[Steatocystoma]]. | |||
*[[Lipoma]]. | |||
*[[Dermatofibroma]]. | |||
*[[Dermal scar]]. | |||
*[[Trichoepithelioma]] ([[trichoblastoma]]). | |||
*[[Clear cell acanthoma]]. | |||
*[[Leiomyoma]]. | |||
Benign melanocytic lesions: | |||
*[[Intradermal nevus]]. | |||
*[[Junctional nevus]]. | |||
*[[Congenital nevus]]. | |||
*[[Clark nevus]]. | |||
*[[Spitz nevus]]. | |||
*[[Pigmented spindle cell nevus of Reed]]. | |||
*[[Blue nevus]]. | |||
Inflammatory skin lesions: | |||
*[[Bullous diseases]]: | |||
**[[Pemphigus vulgaris]]. | |||
**[[Dermatitis herpetiformis]]. | |||
*Interface dermatitis: | |||
**[[Lupus erythematosus]]. | |||
**[[Lichen planus]]. | |||
*Nodular & diffuse: | |||
**[[Cutaneous T-cell lymphoma]]. | |||
**[[Granuloma annulare]]. | |||
**[[Necrobiosis lipoidica]]. | |||
*Psoriasiform diseases: | |||
**[[Psoriasis vulgaris]]. | |||
**[[Lichen simplex chronicus]]. | |||
*[[Panniculitis]]: | |||
**[[Erythema nodosum]]. | |||
**[[Erythema induratum]]. | |||
*[[Vasculitides]]: | |||
**[[Leukocytoclastic vasculitis]]. | |||
Malignant: | |||
*[[Basal cell carcinoma]]. | |||
*[[Squamous cell carcinoma]]. | |||
*[[Malignant melanoma]]. | |||
*[[Merkel cell carcinoma]]. | |||
*[[Dermatofibrosarcoma protuberans]]. | |||
*[[Atypical fibroxanthoma]]. | |||
*[[Leiomyosarcoma]]. | |||
*[[Metastasis]]. | |||
==Endocrine pathology== | |||
===Thyroid gland=== | |||
Benign: | |||
*[[Nodular hyperplasia]]. | |||
*[[Lymphocytic thyroiditis]]. | |||
**[[Hashimoto thyroiditis]]. | |||
*[[Noninvasive follicular thyroid neoplasm with papillary-like nuclear features]] (NIFTP). | |||
Benign - uncommon: | |||
*[[Hyalinizing trabecular tumour]]. | |||
*[[Subacute thyroiditis]]. | |||
Malignant: | |||
*[[Papillary thyroid carcinoma follicular variant]]. | |||
*[[Papillary thyroid carcinoma]]. | |||
Malignant - uncommon: | |||
*[[Papillary thyroid carcinoma columnar cell variant]]. | |||
*[[Papillary thyroid carcinoma tall cell variant]]. | |||
*[[Papillary thyroid carcinoma cribriform-morular variant]]. | |||
*[[Papillary thyroid carcinoma diffuse sclerosing variant]]. | |||
*[[Medullary thyroid carcinoma]]. | |||
*[[Anaplastic thyroid carcinoma]]. | |||
===Thyroid gland - cytology=== | |||
*Benign. | |||
*[[Follicular lesion of undetermined significance]] (FLUS). | |||
*[[Follicular neoplasm]]. | |||
*Suspicious for malignancy. | |||
*Malignant, e.g. [[Thyroid_cytopathology#Papillary_carcinoma|papillary thyroid carcinoma]]. | |||
*Nondiagnostic ''or'' unsatisfactory. | |||
===Parathyroid gland=== | |||
Benign: | |||
*[[Parathyroid hyperplasia]]. | |||
*[[Parathyroid adenoma]]. | |||
Malignant - rare: | |||
*[[Parathyroid carcinoma]]. | |||
===Adrenal gland=== | |||
Benign: | |||
*[[Adrenal cortical adenoma]]. | |||
*[[Adrenal myelolipoma]]. | |||
*[[Hemorrhagic adrenalitis]] (Waterhouse-Friderichsen syndrome). | |||
*[[Adrenal ganglioneuroma]]. | |||
*[[Neuroblastoma]] - [[pediatric pathology]]. | |||
*[[Tuberculosis]]. | |||
Malignant: | |||
*[[Adrenal cortical carcinoma]]. | |||
*[[Pheochromocytoma]]. | |||
*[[Metastasis]]. | |||
==Gastrointestinal pathology== | |||
===Gastrointestinal polyp=== | |||
Benign: | |||
*Normal. | |||
*[[Hyperplastic polyp]]. | |||
*[[Inflammatory pseudopolyp]] ([[inflammatory bowel disease]]). | |||
Pre-malignant: | |||
*[[Tubular adenoma of the gastrointestinal tract|Tubular adenoma]]. | |||
*[[Villous adenoma]]. | |||
*[[Tubulovillous adenoma]]. | |||
*[[Sessile serrated adenoma]]. | |||
Uncommon - pre-malignant: | |||
*[[Traditional serrated adenoma]]. | |||
Uncommon - benign: | |||
*[[Peutz-Jeghers polyp]]. | |||
*[[Juvenile polyp]]. | |||
*[[Inflammatory fibroid polyp]]. | |||
Malignant: | |||
*[[Adenocarcinoma]]. | |||
**[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]]. | |||
===Esophagus=== | |||
Benign: | |||
*[[Gastroesophageal reflux disease]]. | |||
*[[Eosinophilic esophagitis]]. | |||
*[[Barrett esophagus]]. | |||
Benign - uncommon: | |||
*[[Candida esophagitis]]. | |||
*[[Herpes esophagitis]]. | |||
Tumour: | |||
*[[Leiomyoma]]. | |||
*[[Gastrointestinal stromal tumour]] - may be malignant. | |||
*[[Granular cell tumour]] - may be malignant. | |||
Malignant: | |||
*[[Squamous cell carcinoma of the esophagus]] | |||
*[[Esophageal adenocarcinoma|Adenocarcinoma]]. | |||
===Stomach=== | |||
Benign: | |||
*[[Helicobacter pylori gastritis]]. | |||
*[[Gastric intestinal metaplasia|Intestinal metaplasia]]. | |||
*[[Chronic gastritis]]. | |||
*[[Acute gastritis]]. | |||
Pre-malignant: | |||
*[[Gastric dysplasia]]. | |||
Malignant: | |||
*Epithelial: | |||
**Adenocarcinoma, intestinal-type. | |||
**Adenocarcinoma, diffuse-type. | |||
***[[Signet-ring cell carcinoma]]. | |||
**Metastatic carcinoma. | |||
**[[Neuroendocrine tumour]]. | |||
*Mesenchymal: | |||
**[[GIST]]. | |||
*Hematopoietic: | |||
**[[MALT lymphoma]]. | |||
**[[Mantle cell lymphoma]]. | |||
**[[Diffuse large B-cell lymphoma]]. | |||
===Duodenum=== | |||
Benign: | |||
*Normal. | |||
*[[Celiac disease]]. | |||
Pre-malignant: | |||
*[[Tubular adenoma of the gastrointestinal tract|Tubular adenoma]]. | |||
Malignant: | |||
*[[Duodenal adenocarcinoma]]. | |||
Uncommon benign: | |||
*[[Gastric heterotopia of the duodenum]]. | |||
*[[Peptic ulcer disease]]. | |||
*[[Acute duodenitis]]. | |||
*[[Giardiasis]]. | |||
*[[Whipple disease]]. | |||
*[[MAI]] infection. | |||
*[[Pseudomelanosis duodeni]]. | |||
===Colon/rectum=== | |||
Benign: | |||
*Normal. | |||
*[[Colitis]]. | |||
**[[IBD]] - [[Crohn's disease]], [[ulcerative colitis]]. | |||
*[[Hyperplastic polyp]]. | |||
*[[Tubular adenoma of the gastrointestinal tract|Tubular adenoma]]. | |||
*[[Tubulovillous adenoma]]. | |||
*[[Villous adenoma]]. | |||
*[[Sessile serrated adenoma]]. | |||
Benign - uncommon infectious: | |||
*[[Pseudomembranous colitis]]. | |||
*[[Cytomegalovirus colitis]]. | |||
*[[Cryptosporidiosis]]. | |||
*[[Strongyloidiasis]]. | |||
*[[Intestinal spirochetosis]]. | |||
Benign - uncommon: | |||
*[[Lymphocytic colitis]]. | |||
*[[Collagenous colitis]]. | |||
*[[Inflammatory polyp]]. | |||
*[[Juvenile polyp]]. | |||
*[[Peutz-Jeghers polyp]]. | |||
*[[Solitary rectal ulcer]]. | |||
*[[Melanosis coli]]. | |||
*[[Radiation colitis]]. | |||
*[[Diversion colitis]]. | |||
Tumour: | |||
*[[Gastrointestinal stromal tumour]]. | |||
*[[Schwannoma]]. | |||
*[[Lipoma]]. | |||
*[[Neuroendocrine tumour]]. | |||
Malignant: | |||
*[[Colorectal adenocarcinoma]]. | |||
**Medullary carcinoma. | |||
**Mucinous carcinoma. | |||
**Signet ring carcinoma. | |||
*[[Goblet cell carcinoid]]. | |||
*[[metastases|Metastatic tumours]]. | |||
====Appendix==== | |||
Benign: | |||
*[[Appendicitis]]. | |||
*[[Periappendicitis]]. | |||
*[[Crohn's disease]]. | |||
*Normal. | |||
Benign - uncommon: | |||
*[[Enterobius vermicularis]]. | |||
*[[Granulomatous appendicitis]]. | |||
Neoplasm: | |||
*[[Neuroendocrine tumour]]. | |||
*[[Low-grade appendiceal mucinous neoplasm]] (LAMN). | |||
Malignant: | |||
*[[Mucinous adenocarcinoma of the appendix]]. | |||
*[[Goblet cell carcinoid]]. | |||
===Liver=== | |||
Benign: | |||
*[[Steatosis]]. | |||
*[[Steatohepatitis]]. | |||
*[[Hepatitis B]]. | |||
*[[Hepatitis C]]. | |||
Benign - tumour: | |||
*Hepatic hemangioma. | |||
*[[Focal nodular hyperplasia]]. | |||
*[[Hepatocellular adenoma]]. | |||
Malignant: | |||
*[[Liver metastasis]] - usually [[metastatic]] [[adenocarcinoma]]. | |||
*[[Hepatocellular carcinoma]]. | |||
Uncommon benign: | |||
*[[Alpha-1 antitrypsin deficiency]]. | |||
*[[Autoimmune hepatitis]]. | |||
*[[Primary sclerosing cholangitis]], especially in the context of [[UC]]. | |||
*[[Primary biliary cholangitis]]. | |||
*[[Wilson's disease]]. | |||
*[[Hereditary hemochromatosis]]. | |||
*Hepatic infarct. | |||
*[[Hepatitis A]]. | |||
Uncommon malignant: | |||
*[[Cholangiocarcinoma]]. | |||
*[[Angiosarcoma]]. | |||
*[[Epithelioid hemangioendothelioma]]. | |||
===Gallbladder=== | |||
Benign: | |||
*[[Cholelithiasis]]. | |||
*[[Cholesterolosis]]. | |||
*[[Acute cholecystitis]]. | |||
*[[Chronic cholecystitis]]. | |||
*[[Intestinal metaplasia of the gallbladder|Intestinal metaplasia]]. | |||
Uncommon - pre-malignant: | |||
*[[Gallbladder adenoma]]. | |||
Uncommon - malignant: | |||
*[[Carcinoma of the gallbladder]]. | |||
==Genitourinary pathology== | |||
===Tumour kidney=== | |||
Benign: | |||
*[[Normal kidney]]. | |||
*[[Renal oncocytoma]]. | |||
*[[Angiomyolipoma]]. | |||
*[[Papillary adenoma]]. | |||
*[[Clear cell papillary renal cell tumour]] (previously ''clear cell papillary renal cell carcinoma'' or ''clear cell tubulopapillary renal cell carcinoma''). | |||
*[[Renal medullary fibroma]]. | |||
Malignant - common: | |||
*[[Clear cell renal cell carcinoma]]. | |||
*[[Papillary renal cell carcinoma]]. | |||
*[[Chromophobe renal cell carcinoma]]. | |||
*[[Urothelial carcinoma]]. | |||
Malignant - less common: | |||
*[[Collecting duct carcinoma]]. | |||
*[[Renal tumour with Xp11.2 translocation]]. | |||
*[[SMARCB1-deficient renal medullary carcinoma]]. | |||
*[[Renal mucinous tubular and spindle cell carcinoma]]. | |||
*[[SDH-deficient renal cell carcinoma]]. | |||
*[[Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma]]. | |||
*[[Acquired cystic disease-associated renal cell carcinoma]]. | |||
*[[Renal hybrid oncocytic/chromophobe tumour]]. | |||
*[[Tubulocystic renal cell carcinoma]]. | |||
*[[Unclassified renal cell carcinoma]]. | |||
*[[ALK-rearranged renal cell carcinoma]]. | |||
Possibly benign: | |||
*[[Multilocular cystic renal neoplasm of low malignant potential]]. | |||
Uncommon - benign: | |||
*[[Xanthogranulomatous pyelonephritis]]. | |||
*[[Chronic pyelonephritis]]. | |||
*[[Eosinophilic vacuolated tumour]]. | |||
*[[Mixed epithelial stromal tumour]]. | |||
*[[Cystic nephroma]]. | |||
*[[Metanephric adenoma]]. | |||
*[[Low-grade oncocytic tumour]]. | |||
Children - tumours: | |||
*[[Wilms tumour]]. | |||
*[[Clear cell sarcoma of the kidney]]. | |||
*[[Metanephric stromal tumour]]. | |||
*[[Metanephric adenofibroma]]. | |||
*[[Mesoblastic nephroma]]. | |||
*[[Renal rhabdoid tumour]]. | |||
*[[Renal tumour with t(6;11) translocation]]. | |||
===Medical kidney=== | |||
Important/common: | |||
*[[Diabetic nephropathy]]. | |||
*[[Systemic lupus erythematosus]]. | |||
Nephrotic syndrome: | |||
*[[Minimal change disease]]. | |||
*[[Focal segmental glomerulosclerosis]]. | |||
*[[Membranous nephropathy]]. | |||
Nephritic syndrome: | |||
*[[Post-infectious glomerulonephritis]]. | |||
*[[IgA nephropathy]]. | |||
*[[Lupus nephritis]]. | |||
*[[Antiglomerular basement membrane disease]]. | |||
*[[Wegener's granulomatosis]]. | |||
Mixed presentation: | |||
*[[Membranoproliferative glomerulonephritis]] (MPGN). | |||
Cystic disease: | |||
*[[Autosomal dominant polycystic kidney disease]] (ADPKD). | |||
*[[Acquired renal cystic disease]]. | |||
*[[Autosomal recessive polycystic kidney disease]]. | |||
Others: | |||
*[[Fibrillary glomerulopathy]]. | |||
*[[Renal amyloidosis]]. | |||
*[[Thin glomerular basement membrane disease]]. | |||
*[[Alport syndrome]]. | |||
*[[Fabry disease|Fabry's disease]]. | |||
*[[Thrombotic microangiopathy]]. | |||
*[[End-stage kidney]]. | |||
===Prostate gland=== | |||
Benign: | |||
*Normal. | |||
*Chronic inflammation. | |||
*Acute inflammation. | |||
*[[Benign prostatic hyperplasia]] (prostectomy diagnosis only). | |||
*[[Granulomatous prostatitis]]. | |||
Pre-malignant: | |||
*[[High-grade prostatic intraepithelial neoplasia]]. | |||
Suspicious: | |||
*[[Atypical small acinar proliferation]] (atypical glands, suspicious). | |||
Malignant: | |||
*[[Prostate adenocarcinoma|Acinar adenocarcinoma]]. | |||
Waffle category: | |||
*[[Prostatic stromal tumour of uncertain malignant potential]]. | |||
Uncommon - malignant: | |||
*[[Ductal adenocarcinoma of the prostate]]. | |||
*Urothelial carcinoma. | |||
*[[Mucinous prostate carcinoma]]. | |||
*[[Prostatic signet ring cell carcinoma]]. | |||
*[[Sarcomatoid prostate carcinoma]]. | |||
*[[Small cell carcinoma of the prostate gland]]. | |||
*[[Adenoid cystic/basal cell carcinoma of the prostate]]. | |||
*[[Prostatic stromal sarcoma]]. | |||
Mimic benign: | |||
*[[Foamy gland carcinoma]]. | |||
*[[Pseudohyperplastic adenocarcinoma]]. | |||
*[[Atrophic prostate carcinoma]]. | |||
*[[PIN-like prostatic ductal adenocarcinoma]] - mimics HGPIN. | |||
===Urinary bladder=== | |||
Benign: | |||
*[[Inverted urothelial papilloma]]. | |||
*[[Cystitis cystica]]. | |||
*[[Nephrogenic adenoma]]. | |||
Pre-malignant/malignant: | |||
*[[Urothelial dysplasia]]. | |||
*[[Urothelial carcinoma in situ]]. | |||
*[[Low grade papillary urothelial carcinoma]]. | |||
*[[High grade papillary urothelial carcinoma]]. | |||
*Flat [[urothelial carcinoma]]. | |||
Uncommon - benign: | |||
*[[Malakoplakia]]. | |||
*[[Giant cell cystitis]]. | |||
===Urine - cytology=== | |||
Common: | |||
*Negative for malignancy. | |||
*[[Urothelial carcinoma]]. | |||
*[[Polyomavirus]]. | |||
Uncommon: | |||
*[[Squamous cell carcinoma]]. | |||
*[[Adenocarcinoma]]. | |||
===Testis=== | |||
Non-neoplastic: | |||
*[[Testicular abscess]]. | |||
*[[Testicular atrophy]]. | |||
*[[Testicular scar]]. | |||
*[[Sertoli cell nodule]] (Pick's adenoma). | |||
Pre-neoplastic: | |||
*[[Germ cell neoplasia in situ]] (intratubular germ cell neoplasia). | |||
Common tumours: | |||
*[[Seminoma]]. | |||
*[[Embryonal carcinoma]]. | |||
*[[Yolk sac tumour]]. | |||
*[[Teratoma]]. | |||
*[[Mixed germ cell tumour]]. | |||
Less common tumours: | |||
*[[Sertoli cell tumour]]. | |||
*[[Leydig cell tumour]]. | |||
*[[Lymphoma]]. | |||
*[[Choriocarcinoma]]. | |||
*[[Spermatocytic tumour]]. | |||
*[[Malignant mesothelioma]]. | |||
*[[Liposarcoma]]. | |||
*[[Adenocarcinoma of the rete testis]]. | |||
====Associated with testis==== | |||
*[[Spermatocele]]. | |||
*[[Hydrocele testis]]. | |||
*[[Vasitis nodosa]]. | |||
*[[Fibrous pseudotumour of the paratesticular region]]. | |||
Epididymis: | |||
*[[Papillary cystadenoma of the epididymis]]. | |||
*[[Serous cystadenoma]] of the epididymis. | |||
==Gynecologic pathology== | |||
===Uterus=== | |||
Benign: | |||
*[[Fibroids]]. | |||
*[[Adenomyosis]]. | |||
*[[Atrophic endometrium]]. | |||
*[[Uterine prolapse]]. | |||
*[[Proliferative phase endometrium]]. | |||
*[[Secretory phase endometrium]]. | |||
*[[Disordered proliferative endometrium]]. | |||
Pre-malignant: | |||
*[[Simple endometrial hyperplasia]]. | |||
*[[Simple endometrial hyperplasia with atypia]]. | |||
*[[Complex endometrial hyperplasia]]. | |||
*[[Complex endometrial hyperplasia with atypia]]. | |||
Malignant: | |||
*[[Endometrial carcinoma]]. | |||
**[[Endometrioid endometrial carcinoma]]. | |||
**[[Mucinous endometrial carcinoma]]. | |||
**[[Serous endometrial carcinoma]]. | |||
Uncommon - benign: | |||
*Decidua (change of pregnancy). | |||
*[[Arias-Stella reaction]]. | |||
Uncommon - malignant: | |||
*[[Clear cell endometrial carcinoma]]. | |||
*[[Uterine carcinosarcoma|Carcinosarcoma]]. | |||
*[[Endometrial stromal sarcoma]]. | |||
===Cervix - cytology=== | |||
{{Main|Gynecologic cytopathology}} | |||
Benign: | |||
*Normal. | |||
*Candida. | |||
*Endometrial cells >40 years. | |||
Benign not typically reported: | |||
*Atrophy. | |||
*Reactive changes. | |||
*Squamous metaplasia. | |||
*Tubal metaplasia. | |||
*Endometrial cells <40 years. | |||
Uncommon - benign: | |||
*[[HSV]] changes. | |||
*Trichomonas. | |||
*[[Bacterial vaginosis]]. | |||
*[[Actinomycetes]]. | |||
Waffle diagnoses: | |||
*[[Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion]] (ASC-H). | |||
*[[Atypical squamous cells of undetermined significance]] (ASC-US). | |||
*[[Atypical glandular cells]] (AGC). | |||
Pre-malignant/malignant: | |||
*[[LSIL]]. | |||
*[[HSIL]]. | |||
*[[Squamous cell carcinoma]]. | |||
*Adenocarcinoma in situ. | |||
**Endocervical. | |||
**Endometrial. | |||
**Other. | |||
===Ovary=== | |||
Benign: | |||
*[[Serous cystadenoma of the ovary]]. | |||
*[[Mucinous cystadenoma of the ovary]]. | |||
*[[Mature teratoma]]. | |||
*[[Endometriosis]]. | |||
Malignant: | |||
*[[Serous carcinoma of the ovary]]. | |||
*[[Endometrioid carcinoma of the ovary]]. | |||
*[[Mucinous ovarian carcinoma|Mucinous carcinoma]]. | |||
Uncommon - malignant: | |||
*[[Dysgerminoma]]. | |||
*[[Clear cell carcinoma of the ovary]]. | |||
*[[Choriocarcinoma]]. | |||
Other tumours: | |||
*[[Leydig cell tumour]]. | |||
*[[Sertoli-Leydig cell tumour]]. | |||
*[[Adult granulosa cell tumour]]. | |||
*[[Juvenile granulosa cell tumour]]. | |||
*[[Thecoma]]. | |||
*[[Sex cord tumour with annular tubules]]. | |||
*[[Ovarian fibroma]]. | |||
*[[Brenner tumour]]. | |||
===Fallopian tube=== | |||
Benign: | |||
*Paratubal cyst. | |||
*Tubo-ovarian abscess. | |||
*[[Salpingitis]]. | |||
*[[Ectopic pregnancy]]. | |||
*[[Adenomatoid tumour]]. | |||
Malignant: | |||
*[[Serous carcinoma]]. | |||
Uncommon - benign: | |||
*[[Salpingitis isthmica nodosa]]. | |||
==Head and neck== | |||
===General=== | |||
Benign: | |||
*[[Sinonasal papilloma]]. | |||
*[[Vocal cord nodule]]. | |||
Malignant: | |||
*[[Squamous cell carcinoma of the head and neck]]. | |||
*[[Nasopharyngeal carcinoma]]. | |||
*[[HPV-associated squamous cell carcinoma of the head and neck]]. | |||
Uncommon - malignant: | |||
*[[Paraganglioma]] (carotid body tumour). | |||
===Salivary gland=== | |||
Benign: | |||
*[[Pleomorphic adenoma]]. | |||
*[[Warthin tumour]]. | |||
*[[Basal cell adenoma]]. | |||
*[[Oncocytoma of the salivary gland]]. | |||
*[[Canalicular adenoma]]. | |||
Malignant: | |||
*[[Mucoepidermoid carcinoma]]. | |||
*[[Adenoid cystic carcinoma]]. | |||
Uncommon benign: | |||
*[[Benign lymphoepithelial cyst]]. | |||
*[[Basal cell adenoma]]. | |||
*[[Canalicular adenoma]]. | |||
*[[Oncocytoma]]. | |||
Uncommon malignant: | |||
*[[Acinic cell carcinoma]]. | |||
*[[Polymorphous adenocarcinoma]] - previously known as ''polymorphous low-grade adenocarcinoma''. | |||
*[[Carcinoma ex pleomorphic adenoma]]. | |||
*[[Salivary duct carcinoma]]. | |||
*[[Hyalinizing clear cell carcinoma]]. | |||
*[[Epithelial-myoepithelial carcinoma]]. | |||
*[[Secretory carcinoma of the salivary gland]] (mammary analogue secretory carcinoma). | |||
*[[Human papillomavirus-related multiphenotypic sinonasal carcinoma]] (HPV-related carcinoma with adenoid cystic-like features). | |||
==Lymph node== | |||
Benign: | |||
*Normal/resting. | |||
*[[Reactive follicular hyperplasia]]. | |||
*[[Sinus histiocytosis]]. | |||
*[[Hyalinized lymph node]]. | |||
Malignant: | |||
*[[Lymph node metastasis|Metastasis]], esp. [[carcinoma]]. | |||
*[[Follicular lymphoma]]. | |||
*[[Chronic lymphocytic leukemia]]/[[Small cell lymphoma]]. | |||
*[[Diffuse large B cell lymphoma]]. | |||
*[[Nodular sclerosis Hodgkin lymphoma]]. | |||
*[[Mixed cellularity Hodgkin lymphoma]]. | |||
*[[Nodular lymphocyte predominant Hodgkin lymphoma]]. | |||
*[[Lymphocyte-rich Hodgkin lymphoma]]. | |||
*[[Lymphocyte-depleted Hodgkin lymphoma]]. | |||
*[[Marginal zone lymphoma]]. | |||
Benign - uncommon: | |||
*[[Castleman disease]]. | |||
*[[Progressive transformation of germinal centers]]. | |||
*[[Dermatopathic lymphadenopathy]]. | |||
*[[Sarcoidosis]]. | |||
*[[Tuberculosis]]. | |||
*[[Cat-scratch disease]]. | |||
*[[Rosai-Dorfman disease]]. | |||
*[[Kimura disease]]. | |||
*[[Toxoplasmosis]]. | |||
*[[Intranodal palisaded myofibroblastoma]]. | |||
==Neuropathology== | |||
===Brain=== | |||
Benign: | |||
*[[Epidural hemorrhage]]. | |||
*[[Subdural hemorrhage]]. | |||
*[[Subarachnoid hemorrhage]]. | |||
*[[Intracerebral hemorrhage]]. | |||
*[[Duret hemorrhage]]. | |||
*[[Hypoxic-ischemic encephalopathy]]. | |||
*[[Multiple sclerosis]]. | |||
*[[Colloid cyst]]. | |||
*[[Cerebral amyloid angiopathy]]. | |||
Pediatric - tumour: | |||
*[[Pilocytic astrocytoma]]. | |||
*[[Neuroblastoma]]. | |||
*[[Retinoblastoma]]. | |||
*[[Ependymoma]]. | |||
Adult - tumour: | |||
*[[Meningioma]]. | |||
*[[Schwannoma]]. | |||
*[[Diffuse astrocytoma]]. | |||
*[[Anaplastic astrocytoma]]. | |||
*[[Glioblastoma]]. | |||
*[[Myxopapillary ependymoma]]. | |||
*[[Pituitary adenoma]]. | |||
*[[Adamantinomatous craniopharyngioma]]. | |||
*[[Papillary craniopharyngioma]]. | |||
*[[Oligodendroglioma]]. | |||
*[[Brain metastasis]]. | |||
===Neurodegenerative=== | |||
*[[Alzheimer disease]]. | |||
*[[Creutzfeldt-Jakob disease]]. | |||
*[[Parkinson disease]]. | |||
*[[Multiple system atrophy]]. | |||
*[[Dementia with Lewy bodies]]. | |||
*[[Multiple system atrophy]]. | |||
*[[Chronic traumatic encephalopathy]]. | |||
*[[Huntington disease]]. | |||
===Muscle=== | |||
*[[Dermatomyositis]]. | |||
*[[Polymyositis]]. | |||
*[[Muscular dystrophy]]. | |||
*[[Amyotrophic lateral sclerosis]]. | |||
*[[Inclusion body myositis]]. | |||
*[[Drug-induced rhabdomyolysis]]. | |||
==Pulmonary pathology== | |||
Benign: | |||
*Normal. | |||
*Acute [[bronchopneumonia]]. | |||
*[[Diffuse alveolar damage]] - acute phase, organizing phase, resolution. | |||
*[[Emphysema]] - centrilobular, panlobular. | |||
*[[Asthma]]. | |||
*[[Aspiration pneumonia]]. | |||
*[[Pulmonary meningothelial-like nodule]]. | |||
Malignant: | |||
*[[Lung adenocarcinoma|Adenocarcinoma]]. | |||
*[[Squamous carcinoma of the lung]]. | |||
*[[Small cell carcinoma of the lung]]. | |||
*[[Lung metastasis]]. | |||
Uncommon - granulomatous: | |||
*[[Tuberculosis]]. | |||
*[[Sarcoidosis]]. | |||
*Fungal infections (e.g. [[aspergillosis]]). | |||
Uncommon - benign other: | |||
*[[Carcinoid tumourlet]]. | |||
*[[Typical lung carcinoid tumour]]. | |||
*[[Atypical lung carcinoid tumour]]. | |||
*[[Solitary fibrous tumour]] - esp. pleural. | |||
*[[Lymphangioleiomyomatosis]]. | |||
*[[Pulmonary Langerhans cell histiocytosis]]. | |||
*[[Bronchogenic cyst]]. | |||
*[[Congenital pulmonary airway malformation]] (CPAM). | |||
*[[Extralobar sequestration]]. | |||
*[[Intralobar sequestration]]. | |||
*[[Asbestosis]]. | |||
*[[Silicosis]]. | |||
*Coal worker's pneumonconiosis. | |||
*[[Pulmonary alveolar proteinosis]]. | |||
*[[Eosinophilic pneumonia]]. | |||
*[[Goodpasture disease]]. | |||
*[[Wegener's granulomatosis]]. | |||
*Radiation pneumonitis. | |||
*Drug toxicity, e.g. amiodarone, bleomycin. | |||
*Infectious - [[blastomycosis]], [[cryptococcosis]], [[histoplasmosis]], [[pneumocystis pneumonia]]. | |||
Uncommon - vascular: | |||
*[[Pulmonary hypertension]]. | |||
*[[Vasculitides]] - see ''cardiovascular'' section. | |||
Uncommon - [[diffuse lung diseases|idiopathic interstitial pneumonias]]: | |||
*[[Usual interstitial pneumonia]] (UIP). | |||
*[[Non-specific interstitial pneumonia]] (NSIP). | |||
*[[Lymphocytic interstitial pneumonia]] (LIP). | |||
*[[Cryptogenic organizing pneumonia]] (BOOP). | |||
*[[Respiratory bronchiolitis-associated interstitial lung disease]] (RB-ILD). | |||
*[[Desquamative interstitial pneumonia]] (DIP). | |||
Uncommon - malignant: | |||
*[[Malignant mesothelioma]]. | |||
==Spleen== | |||
Benign: | |||
*Trauma. | |||
*Normal. | |||
*Enlargement due to [[cirrhosis]] or other causes of [[portal hypertension]]. | |||
*[[Mononucleosis]]. | |||
Benign - rare: | |||
*[[Hemophagocytic syndrome]]. | |||
Malignant - common: | |||
*[[Diffuse large B-cell lymphoma]]. | |||
*[[Splenic marginal zone lymphoma]]. | |||
*[[Follicular lymphoma]]. | |||
Malignant - others: | |||
*[[Hairy cell leukemia]]. | |||
*[[Hepatosplenic T-cell lymphoma]]. | |||
==Placenta== | |||
*Normal. | |||
*[[Chorioamnionitis]]. | |||
**[[Funisitis]]. | |||
*[[Meconium]]. | |||
*[[Placentomegaly]]. | |||
*[[Placental infarction]]. | |||
Less common: | |||
*[[TORCH infections]]. | |||
*[[Chorangioma]]. | |||
*[[Chorangiosis]]. | |||
*[[Villitis of unknown etiology]]. | |||
*[[Chronic intervillitis]]. | |||
*[[Two vessel umbilical cord]]. | |||
*[[Maternal floor infarction]]. | |||
*[[Fetal thrombotic vasculopathy]]. | |||
*[[Hypertrophic decidual vasculopathy]]. | |||
=Pathologic characteristics= | =Pathologic characteristics= | ||
Line 6: | Line 972: | ||
*[[Breast]] tumours. | *[[Breast]] tumours. | ||
==Tumours with lymphocytes== | ==Nodule-forming lymphoma== | ||
Malignant: | |||
*[[Follicular lymphoma]]. | |||
*[[Small cell lymphoma]]. | |||
*[[Nodular lymphocyte predominant Hodgkin lymphoma]]. | |||
*[[Mantle cell lymphoma]]. | |||
==Nuclear features== | |||
===Pseudostratified nuclei=== | |||
Tumours that commonly have pseudostratified nuclei: | |||
*[[Colorectal carcinoma]]. | |||
*[[Endometrioid endometrial carcinoma]]. | |||
===Pseudoinclusions=== | |||
{{Main|Nuclear pseudoinclusions}} | |||
==Cytoplasmic features== | |||
===Eosinophilic cytoplasm=== | |||
*[[Squamous cell carcinoma]]. | |||
*[[Oncocytoma]]/oncocytic tumours. | |||
*Apocrine tumours. | |||
*[[Anaplastic large cell lymphoma]]. | |||
===Clear cytoplasm=== | |||
{{Main|Clear cell tumours}} | |||
==Cells== | |||
===Tumours with lymphocytes=== | |||
*[[Seminoma]]. | *[[Seminoma]]. | ||
*[[Acinic cell carcinoma]]. | *[[Acinic cell carcinoma]]. | ||
Line 12: | Line 1,005: | ||
*[[Lymphoepithelioma-like carcinoma]]. | *[[Lymphoepithelioma-like carcinoma]]. | ||
*[[Medullary breast carcinoma]]. | *[[Medullary breast carcinoma]]. | ||
*[[Thymoma]]. | |||
*[[Lymphoma]] - [[Hodgkin lymphoma|Hodgkin]] and [[Non-Hodgkin lymphoma|non-Hodgkin]]. | |||
*[[Follicular dendritic cell sarcoma]]. | |||
= | ===Giant cells=== | ||
==Giant cells== | |||
{{Main|Giant cell lesions}} | {{Main|Giant cell lesions}} | ||
= | ===Many eosinophils=== | ||
*Infection - esp. fungal. | |||
*[[Drug reaction]]. | |||
==Many eosinophils== | *[[Inflammatory fibroid polyp]]. | ||
*Infection. | *[[Hodgkin lymphoma]]. | ||
*[[Churg-Strauss syndrome]]. | |||
*[[Langerhans cell histiocytosis]]. | *[[Langerhans cell histiocytosis]]. | ||
*[[Kimura disease]]. | *[[Kimura disease]]. | ||
Site specific: | Site specific: | ||
*[[Eosinophilic | *[[Eosinophilic esophagitis]]. | ||
*[[Eosinophilic gastritis]]. | |||
*[[Eosinophilic colitis]]. | |||
*[[Pulmonary Langerhans cell histiocytosis]]. | *[[Pulmonary Langerhans cell histiocytosis]]. | ||
*[[Angiolymphoid hyperplasia with eosinophilia]] (ALHE) - skin. | |||
===Red blood cell extravasation=== | |||
*Hemorrhage. | |||
*[[Vasculitis]]. | |||
*[[Nodular fasciitis]]. | |||
*[[Intranodal palisaded myofibroblastoma]]. | |||
*[[Kaposi sarcoma]]. | |||
==Structures== | |||
===Psammoma bodies=== | |||
{{Main|Psammoma bodies}} | |||
==Myxoid lesions== | |||
{{Main|Myxoid lesions}} | |||
==Architecture== | |||
===Classically nested=== | |||
*[[Paraganglioma]]. | |||
*[[Meningioma]]. | |||
*[[Brenner tumour]]. | |||
*[[SCTAT]]. | |||
===Stroma rich tumours=== | |||
*[[Cholangiocarcinoma]]. | |||
*[[Fibrolamellar hepatocellular carcinoma]]. | |||
*[[Mesothelioma]] - lung. | |||
*[[Hyalinizing trabecular tumour]] - thyroid. | |||
*[[Hyalinizing clear cell carcinoma]] - salivary gland. | |||
===Spindle cell lesions=== | |||
{{Main|Spindle cell lesions}} | |||
====Spindle cell lesions in neuropathology==== | |||
*[[Schwannoma]]. | |||
*[[Gliosarcoma]]. | |||
==Frustration lists== | |||
The following are diagnoses to think about if the answer isn't apparent. | |||
===General frustration list=== | |||
If the pathology isn't apparent... | |||
*[[Neurofibroma]]. | |||
*[[Amyloidosis]]. | |||
*[[Granular cell tumour]]. | |||
*[[Adenomatoid tumour]]. | |||
*[[Angiosarcoma]]. | |||
*[[Pheochromocytoma]]. | |||
*[[Plasma cell neoplasm]]. | |||
Memory device: ''NAGAAPP''. | |||
===CNS frustration list=== | |||
*[[Meningioma]]. | |||
===Head & neck frustration list=== | |||
*[[Myoepithelioma]]. | |||
*[[Mucoepidermoid carcinoma]]. | |||
*[[Polymorphous low-grade adenocarcinoma]]. | |||
===Colonic biopsies frustration list=== | |||
*[[CMV colitis]]. | |||
*[[Cryptosporidiosis]]. | |||
*[[Intestinal spirochetosis]]. | |||
*[[Lymphocytic colitis]]. | |||
*[[Collagenous colitis]]. | |||
=See also= | =See also= |
edits