48,470
edits
Difference between revisions of "Lobular capillary hemangioma"
Jump to navigation
Jump to search
Lobular capillary hemangioma (view source)
Revision as of 18:52, 18 January 2022
, 18:52, 18 January 2022→Alternate - tongue
(→IHC) |
|||
| (5 intermediate revisions by the same user not shown) | |||
| Line 7: | Line 7: | ||
| Micro = polypoid ''or'' peduculated lesion, vascular - with plump endothelium, usu. thinned epithelium or ulcerated, lobular arrangement of vascular (seen at low power) | | Micro = polypoid ''or'' peduculated lesion, vascular - with plump endothelium, usu. thinned epithelium or ulcerated, lobular arrangement of vascular (seen at low power) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[capillary hemangioma]], [[myopericytoma]] (?), [[bacillary angiomatosis]] | | LMDDx = [[capillary hemangioma]], [[myopericytoma]] (?), [[bacillary angiomatosis]], [[traumatic ulcerative granuloma with stromal eosinophilia]] - esp. for tongue lesions | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
| Line 32: | Line 32: | ||
'''Lobular capillary hemangioma''', also known as '''pyogenic granuloma''',<ref name=pmid21839350>{{Cite journal | last1 = Baglin | first1 = AC. | title = [Vascular tumors and pseudotumors. Pyogenic granuloma (lobular capillary hemangioma)]. | journal = Ann Pathol | volume = 31 | issue = 4 | pages = 266-70 | month = Aug | year = 2011 | doi = 10.1016/j.annpat.2011.05.014 | PMID = 21839350 }}</ref> a benign head and neck lesion that can mimic malignancy. | '''Lobular capillary hemangioma''', also known as '''pyogenic granuloma''',<ref name=pmid21839350>{{Cite journal | last1 = Baglin | first1 = AC. | title = [Vascular tumors and pseudotumors. Pyogenic granuloma (lobular capillary hemangioma)]. | journal = Ann Pathol | volume = 31 | issue = 4 | pages = 266-70 | month = Aug | year = 2011 | doi = 10.1016/j.annpat.2011.05.014 | PMID = 21839350 }}</ref> a benign head and neck lesion that can mimic malignancy. | ||
On occasion it is referred to as ''pregnancy tumour''. | |||
==General== | ==General== | ||
*Seen in children, young adults, pregnant women. | *Seen in children, young adults, pregnant women. | ||
| Line 66: | Line 66: | ||
*[[Myopericytoma]] (???). | *[[Myopericytoma]] (???). | ||
*[[Bacillary angiomatosis]].<ref name=pmid16310070>{{Cite journal | last1 = Levy | first1 = I. | last2 = Rolain | first2 = JM. | last3 = Lepidi | first3 = H. | last4 = Raoult | first4 = D. | last5 = Feinmesser | first5 = M. | last6 = Lapidoth | first6 = M. | last7 = Ben-Amitai | first7 = D. | title = Is pyogenic granuloma associated with Bartonella infection? | journal = J Am Acad Dermatol | volume = 53 | issue = 6 | pages = 1065-6 | month = Dec | year = 2005 | doi = 10.1016/j.jaad.2005.08.046 | PMID = 16310070 }}</ref> | *[[Bacillary angiomatosis]].<ref name=pmid16310070>{{Cite journal | last1 = Levy | first1 = I. | last2 = Rolain | first2 = JM. | last3 = Lepidi | first3 = H. | last4 = Raoult | first4 = D. | last5 = Feinmesser | first5 = M. | last6 = Lapidoth | first6 = M. | last7 = Ben-Amitai | first7 = D. | title = Is pyogenic granuloma associated with Bartonella infection? | journal = J Am Acad Dermatol | volume = 53 | issue = 6 | pages = 1065-6 | month = Dec | year = 2005 | doi = 10.1016/j.jaad.2005.08.046 | PMID = 16310070 }}</ref> | ||
*[[Traumatic ulcerative granuloma with stromal eosinophilia]] - abundant [[eosinophil]]s. | |||
Why it is not... | Why it is not... | ||
| Line 88: | Line 89: | ||
==Sign out== | ==Sign out== | ||
<pre> | |||
Tongue Lesion, Excision: | |||
- Lobular capillary hemangioma (pyogenic granuloma). | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
TONGUE, LEFT LATERAL, BIOPSY: | TONGUE, LEFT LATERAL, BIOPSY: | ||
- LOBULAR CAPILLARY HEMANGIOMA (PYOGENIC GRANULOMA).</pre> | - LOBULAR CAPILLARY HEMANGIOMA (PYOGENIC GRANULOMA). | ||
</pre> | |||
<pre> | |||
LESION, POSTERIOR TO LEFT EAR, EXCISION: | |||
- LOBULAR CAPILLARY HEMANGIOMA (PYOGENIC GRANULOMA). | |||
COMMENT: | |||
The lesion stains as follows: | |||
POSITIVE: SMA, CD31. | |||
NEGATIVE: S-100, HMB-45. | |||
</pre> | |||
===Micro=== | ===Micro=== | ||
The sections shows a pendunculated vascular lesion with small capillaries arranged in a lobular fashion. The endothelial cells of the lesion show no atypia. The overlying acanthotic epidermis has hyperkeratosis and hypergranulosis, and is focally ulcerated and impetiginized. There is no significant keratocyte atypia. No melanocytic nests are seen. The dermis has a mild perivascular lymphoplasmacytic infiltrate. The lesion is excised in the plane of section. | The sections shows a pendunculated vascular lesion with small capillaries arranged in a lobular fashion. The endothelial cells of the lesion show no atypia. The overlying acanthotic epidermis has hyperkeratosis and hypergranulosis, and is focally ulcerated and impetiginized. There is no significant keratocyte atypia. No melanocytic nests are seen. The dermis has a mild perivascular lymphoplasmacytic infiltrate. The lesion is excised in the plane of section. | ||
====Alternate - tongue==== | |||
The sections show a pendunculated vascular lesion with small capillaries arranged in a lobular fashion. The endothelial cells of the lesion show no significant atypia. The overlying epithelium is largely eroded. There is no significant keratocyte atypia. The lesion is excised in the plane of section. | |||
==See also== | ==See also== | ||