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Difference between revisions of "Liver neoplasms"
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→Hepatocellular carcinoma
(→Tabular comparison: more) |
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*Commonly abbreviated ''HCC''. | *Commonly abbreviated ''HCC''. | ||
===Clinical=== | ====Clinical==== | ||
*Serum AFP elevated - in approx. 50% of patients.<ref>{{Ref GLP|588}}</ref> | *Serum AFP elevated - in approx. 50% of patients.<ref>{{Ref GLP|588}}</ref> | ||
*Treatments: RFA (radiofrequency ablation), ethanol ablation, liver resection, liver transplant.<ref name=emed_hcc>[http://emedicine.medscape.com/article/282814-overview http://emedicine.medscape.com/article/282814-overview]</ref> | *Treatments: RFA (radiofrequency ablation), ethanol ablation, liver resection, liver transplant.<ref name=emed_hcc>[http://emedicine.medscape.com/article/282814-overview http://emedicine.medscape.com/article/282814-overview]</ref> | ||
*Mean survival at time of diagnosis ~6 months.<ref name=emed_hcc/> | *Mean survival at time of diagnosis ~6 months.<ref name=emed_hcc/> | ||
===Epidemiology=== | ====Epidemiology==== | ||
*Highest where prevalence of hepatitis B virus (HBV) is high.<ref name=Ref_PBoD924>{{Ref PBoD|924}}</ref> | *Highest where prevalence of hepatitis B virus (HBV) is high.<ref name=Ref_PBoD924>{{Ref PBoD|924}}</ref> | ||
*HCC generally arises in the setting of cirrhosis. | *HCC generally arises in the setting of cirrhosis. | ||
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**Graunular eosinophilic cytoplasm. | **Graunular eosinophilic cytoplasm. | ||
*Layered dense collagen bundles. | *Layered dense collagen bundles. | ||
====Sclerosing HCC==== | |||
Features: | |||
*Fibrosis. (???) | |||
Notes: | |||
*Seen in non-cirrhotic livers. | |||
===Grading=== | ===Grading=== | ||