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Difference between revisions of "Liver neoplasms"
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→Microscopic: +IHC
m (→Subtypes) |
(→Microscopic: +IHC) |
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| Line 282: | Line 282: | ||
*+/-Mesenchymal component | *+/-Mesenchymal component | ||
**Immature fibrous tissue, osteoid or cartilage. | **Immature fibrous tissue, osteoid or cartilage. | ||
DDx: | |||
*[[Small round cell tumours]]. | |||
*[[Teratoma]]. | |||
*[[Hepatocellular carcinoma]]. | |||
Images: | Images: | ||
| Line 299: | Line 304: | ||
**# With teratoid features. | **# With teratoid features. | ||
**# Without teratoid features. | **# Without teratoid features. | ||
===IHC=== | |||
*Alpha-fetoprotein +ve. | |||
*Hepatocyte specific antigen +ve esp. in fetal component.<ref name=pmid16647953>{{Cite journal | last1 = Halász | first1 = J. | last2 = Holczbauer | first2 = A. | last3 = Páska | first3 = C. | last4 = Kovács | first4 = M. | last5 = Benyó | first5 = G. | last6 = Verebély | first6 = T. | last7 = Schaff | first7 = Z. | last8 = Kiss | first8 = A. | title = Claudin-1 and claudin-2 differentiate fetal and embryonal components in human hepatoblastoma. | journal = Hum Pathol | volume = 37 | issue = 5 | pages = 555-61 | month = May | year = 2006 | doi = 10.1016/j.humpath.2005.12.015 | PMID = 16647953 }}</ref> | |||
*Beta-catenin +ve (cytoplasmic and nuclear).<ref name=pmid16647953/> | |||
==Hepatocellular carcinoma== | ==Hepatocellular carcinoma== | ||