Difference between revisions of "Leukemia"

Leukemia (view source)

146 bytes added , 21:26, 27 July 2015

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 **Fusion transcripts: PML<ref name=omim102578>{{OMIM|102578}}</ref>-RARA.<ref name=omim180240>{{OMIM|180240}}</ref>
+====General====
+Clinical:
+*Associated with [[DIC]].
+*Treatment: all-trans retinoic acid (ATRA).
+Variants:
+*t(11;17) -- ATRA doesn't work.<ref>{{Ref APBR|623 Q2}}</ref>
+*t(17;17) -- ATRA doesn't work.
+*t(5;17). (???)
+====Microscopic====
 Comes in two flavours.
@@ Line 133: / Line 144: @@
 *Absence of granules on light microscopy.
-Images:
+=====Images=====
+<gallery>
+Image:Faggot cell in AML-M3.jpg |Faggot cell in AML-M3. (WC)
+</gallery>
+www:
 *[http://path.upmc.edu/cases/case457/images/fig01.jpg AML - showing Auer rods (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case457.html http://path.upmc.edu/cases/case457.html]. Accessed on: 21 January 2012.</ref>
 *[http://path.upmc.edu/cases/case705.html APML - several images (upmc.edu)].
-IHC:
+====IHC====
 *CD2 +ve, CD34 +ve/-ve, CD56 +ve/-ve.
-[[Flow cytometry]]:
+====[[Flow cytometry]]====
 *CD34 -ve, HLA-DR -ve.
 *CD33 +ve, CD13 +ve/-ve, CD117 +ve (weak), CD56 +ve/-ve.
-Clinical:
-*Associated with [[DIC]].
-*Treatment: all-trans retinoic acid (ATRA).
-Variants:
-*t(11;17) -- ATRA doesn't work.<ref>{{Ref APBR|623 Q2}}</ref>
-*t(17;17) -- ATRA doesn't work.
-*t(5;17). (???)
 ===Acute myeloid leukemia with t(9;11)===