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Difference between revisions of "Large epithelioid tumours"
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[[Image:Epithelioid angiosarcoma - very high mag.jpg|thumb|200px|right|A large epithelioid tumour ([[epithelioid angiosarcoma]]). [[H&E stain]].]] | |||
'''Large epithelioid tumours''' are common and represent a large [[differential diagnosis]] when viewed generally. | '''Large epithelioid tumours''' are common and represent a large [[differential diagnosis]] when viewed generally. | ||
[[Malignant]] epithelioid lesions are often [[carcinoma]]s... but may be a large number different tumours. | |||
A more general discussion of epithelioid lesions is in the ''[[epithelioid cell lesions]]'' article. Small epithelioid lesions are dealt with in the ''[[small round cell tumours]]'' article. | A more general discussion of epithelioid lesions is in the ''[[epithelioid cell lesions]]'' article. Small epithelioid lesions are dealt with in the ''[[small round cell tumours]]'' article. | ||
==General differential diagnosis== | ==General differential diagnosis== | ||
Adapted from ''Miller'' with modifications:<ref name=miller>Miller RT. (Sep 2013). ''Atlantic Diagnostic Immunohistochemistry Symposium''. St. John's, NL, Canada.</ref> | |||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
! Tumour | ! Tumour | ||
| Line 43: | Line 47: | ||
| [[Myoepithelioma of soft tissue]] | | [[Myoepithelioma of soft tissue]] | ||
| Epithelial tumours | | Epithelial tumours | ||
| may mimic [[extraskeletal myxoid chondrosarcoma]] or proximal variant of [[ | | may mimic [[extraskeletal myxoid chondrosarcoma]] or proximal variant of [[epithelioid sarcoma]] | ||
|- | |- | ||
| [[Acinar cell carcinoma]] | | [[Acinar cell carcinoma]] | ||
| Line 205: | Line 209: | ||
| also [[pheochromocytoma]] | | also [[pheochromocytoma]] | ||
|- | |- | ||
| [[ | | High grade [[olfactory neuroblastoma]] | ||
| Neural - Neuroendocrine - Neuraxis Tumours | | Neural - Neuroendocrine - Neuraxis Tumours | ||
| | | | ||
|- | |- | ||
| [[ | | Epithelioid [[MPNST]] | ||
| Neural - Neuroendocrine - Neuraxis Tumours | | Neural - Neuroendocrine - Neuraxis Tumours | ||
| reported to have focal melanocytic differentiation in some cases{{fact}} | | reported to have focal melanocytic differentiation in some cases{{fact}} | ||
| Line 261: | Line 265: | ||
| | | | ||
|- | |- | ||
| [[ | | [[Rhabdomyosarcoma]], not otherwise specified ([[pleomorphic rhabdomyosarcoma]]) | ||
| Muscle-related tumours | | Muscle-related tumours | ||
| | | | ||
| Line 293: | Line 297: | ||
| | | | ||
|- | |- | ||
| [[ | | [[Epithelioid sarcoma-like hemangioendothelioma]] | ||
| Vascular tumours | | Vascular tumours | ||
| | | <ref name=pmid12502927>{{Cite journal | last1 = Billings | first1 = SD. | last2 = Folpe | first2 = AL. | last3 = Weiss | first3 = SW. | title = Epithelioid sarcoma-like hemangioendothelioma. | journal = Am J Surg Pathol | volume = 27 | issue = 1 | pages = 48-57 | month = Jan | year = 2003 | doi = | PMID = 12502927 }}</ref> | ||
|- | |- | ||
| [[Composite hemangioendothelioma]] | | [[Composite hemangioendothelioma]] | ||
| Line 413: | Line 417: | ||
| | | | ||
|- | |- | ||
| [[ | | Epithelioid [[osteosarcoma]] | ||
| Chondro-osseous tumours | | Chondro-osseous tumours | ||
| | | <ref>{{Cite journal | last1 = Amanatullah | first1 = DF. | last2 = Ngann | first2 = KK. | last3 = Borys | first3 = D. | last4 = Tamurian | first4 = RM. | title = Progression of aggressive metastatic carcinosarcoma after treatment of epithelioid osteosarcoma. | journal = Orthopedics | volume = 33 | issue = 6 | pages = 445 | month = Jun | year = 2010 | doi = 10.3928/01477447-20100429-26 | PMID = 20806764 }}</ref> | ||
|- | |- | ||
| [[Extraskeletal myxoid chondrosarcoma, high grade | | [[Extraskeletal myxoid chondrosarcoma]], high grade | ||
| Chondro-osseous tumours | | Chondro-osseous tumours | ||
| | | | ||