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Difference between revisions of "Juxtaglomerular cell tumour"
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*[[Epithelioid angiomyolipoma]]. | *[[Epithelioid angiomyolipoma]]. | ||
*[[Chromophobe renal cell carcinoma]], eosinophilic variant.{{fact}} | *[[Chromophobe renal cell carcinoma]], eosinophilic variant.{{fact}} | ||
Note - some similarities with: | |||
*[[Solitary fibrous tumour]]. | |||
*[[Glomus tumour]]. | |||
===Images=== | ===Images=== | ||
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==Stains== | ==Stains== | ||
Cytoplasmic granules.<ref name=pmid436071>{{Cite journal | last1 = Hanna | first1 = W. | last2 = Tepperman | first2 = B. | last3 = Logan | first3 = AG. | last4 = Robinette | first4 = MA. | last5 = Colapinto | first5 = R. | last6 = Phillips | first6 = MJ. | title = Juxtaglomerular cell tumour (reninoma) with paroxysmal hypertension. | journal = Can Med Assoc J | volume = 120 | issue = 8 | pages = 957-9 | month = Apr | year = 1979 | doi = | PMID = 436071 PMC = 1819229 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819229/?tool=pubmed }}</ref> | Cytoplasmic granules.<ref name=pmid436071>{{Cite journal | last1 = Hanna | first1 = W. | last2 = Tepperman | first2 = B. | last3 = Logan | first3 = AG. | last4 = Robinette | first4 = MA. | last5 = Colapinto | first5 = R. | last6 = Phillips | first6 = MJ. | title = Juxtaglomerular cell tumour (reninoma) with paroxysmal hypertension. | journal = Can Med Assoc J | volume = 120 | issue = 8 | pages = 957-9 | month = Apr | year = 1979 | doi = | PMID = 436071 | PMC = 1819229 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819229/?tool=pubmed }}</ref> | ||
*PAS +ve. | *PAS +ve. | ||
*PASD +ve. | *PASD +ve. | ||
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*Vimentin +ve. | *Vimentin +ve. | ||
*Actin +ve. | *Actin +ve. | ||
*HMB-45 -ve.<ref name=pmid21191395/> | *HMB-45 -ve.<ref name=pmid21191395/> | ||
| Line 82: | Line 85: | ||
*Synaptophysin -ve. | *Synaptophysin -ve. | ||
*NSE -ve. | *NSE -ve. | ||
*CAM5.2 +ve.<ref name=pmid21871063/> ‡ | |||
*CK7 +ve.<ref name=pmid21871063/> ‡ | |||
Note: | |||
*‡ Negative keratin staining reported by Chao ''et al.''.<ref name=pmid21191395>{{Cite journal | last1 = Chao | first1 = CT. | last2 = Chang | first2 = FC. | last3 = Wu | first3 = VC. | last4 = Chen | first4 = JC. | title = Reninoma. | journal = Kidney Int | volume = 79 | issue = 2 | pages = 260 | month = Jan | year = 2011 | doi = 10.1038/ki.2010.445 | PMID = 21191395 }}</ref> | |||
==EM== | ==EM== | ||
Features: | Features: | ||
*Vesicles - contain renin.<ref name=upmc29>URL: [http://path.upmc.edu/cases/case29/micro.html http://path.upmc.edu/cases/case29/micro.html]. Accessed on: 18 December 2011.</ref> | *Vesicles - contain renin.<ref name=upmc29>URL: [http://path.upmc.edu/cases/case29/micro.html http://path.upmc.edu/cases/case29/micro.html]. Accessed on: 18 December 2011.</ref> | ||
==Molecular== | |||
*NOTCH1 rearrangement.<ref>PMID: 37749094</ref> | |||
==See also== | ==See also== | ||
*[[Kidney tumours]]. | *[[Kidney tumours]]. | ||
*[[Renal tumours with eosinophilic cytoplasm]]. | |||
==References== | ==References== | ||