Account-creators
179
edits
Difference between revisions of "Juvenile granulosa cell tumour"
Jump to navigation
Jump to search
Juvenile granulosa cell tumour (view source)
Revision as of 17:43, 2 January 2017
, 17:43, 2 January 2017→Images: added a case
(→Images: added a case) |
|||
| (6 intermediate revisions by one other user not shown) | |||
| Line 3: | Line 3: | ||
| Image = Juvenile_granulosa_cell_tumour_-_very_high_mag.jpg | | Image = Juvenile_granulosa_cell_tumour_-_very_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Juvenile granulosa cell tumour. [[H&E stain]]. | | Caption = Juvenile granulosa cell tumour. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = microcystic spaces, cuboidal-to-polygonal cells in sheets or stands or cords, with moderate-to-marked nuclear atypia, and basophilic cytoplasm | | Micro = microcystic spaces, cuboidal-to-polygonal cells in sheets or stands or cords, with moderate-to-marked nuclear atypia, and basophilic cytoplasm | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[Brenner tumour]] | | LMDDx = [[Brenner tumour]], [[small cell carcinoma of hypercalcemic type]] | ||
| Stains = | | Stains = | ||
| IHC = inhibin +ve, calretinin +ve | | IHC = inhibin +ve, calretinin +ve | ||
| Line 59: | Line 59: | ||
DDx: | DDx: | ||
*[[Brenner tumour]]. | *[[Brenner tumour]]. | ||
*[[Adult granulosa cell tumour]]. | |||
*[[Small cell carcinoma of hypercalcemic type]].<ref name=pmid21993272>{{Cite journal | last1 = Bárcena | first1 = C. | last2 = Oliva | first2 = E. | title = WT1 expression in the female genital tract. | journal = Adv Anat Pathol | volume = 18 | issue = 6 | pages = 454-65 | month = Nov | year = 2011 | doi = 10.1097/PAP.0b013e318234aaed | PMID = 21993272 }}</ref> | |||
===Images=== | ===Images=== | ||
| Line 66: | Line 68: | ||
Image:Juvenile_granulosa_cell_tumour_-_very_high_mag.jpg | Juvenile granulosa cell tumour - very high mag. (WC) | Image:Juvenile_granulosa_cell_tumour_-_very_high_mag.jpg | Juvenile granulosa cell tumour - very high mag. (WC) | ||
</gallery> | </gallery> | ||
[[File:3 13627319654987 sl 1.png| Juvenile granulosa cell tumor]] | |||
[[File:3 13627319654987 sl 2.png| Juvenile granulosa cell tumor]] | |||
[[File:3 13627319654987 sl 3.png| Juvenile granulosa cell tumor]] | |||
[[File:3 13627319654987 sl 4.png| Juvenile granulosa cell tumor]] | |||
Juvenile granulosa cell tumor of ovary of child. A. A pink tumor shows cyst-like areas with occasional nodules at low power. B. Tumor cells haphazardly spread without longitudinal grooves, with small nucleoli, in an edematous background. C. The cysts are in fact follicles, some producing, as here, the typical basophilic fluid. D. In some regions, abundant pink cytoplasm is obvious. | |||
==IHC== | ==IHC== | ||
| Line 74: | Line 81: | ||
*CD34 -ve (0 +ve/12 cases<ref name=pmid20349790/>). | *CD34 -ve (0 +ve/12 cases<ref name=pmid20349790/>). | ||
*Vimentin +ve (11 +ve/12 cases<ref name=pmid20349790/>). | *Vimentin +ve (11 +ve/12 cases<ref name=pmid20349790/>). | ||
*CD99 +ve.<ref name=pmid17387475>{{Cite journal | last1 = Schmidt | first1 = D. | last2 = Kommoss | first2 = F. | title = [Diagnosis and differential diagnosis of granulosa cell tumor]. | journal = Pathologe | volume = 28 | issue = 3 | pages = 195-202 | month = May | year = 2007 | doi = 10.1007/s00292-007-0908-8 | PMID = 17387475 }}</ref> | |||
==Molecular== | ==Molecular== | ||