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Difference between revisions of "Inverted urothelial papilloma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Inverted_papilloma_high_mag.jpg | |||
| Width = | |||
| Caption = Inverted urothelial papilloma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = like papillomas... but grow downward; '''never''' have an exophytic component; nests have peripheral palisading of nuclei - '''important''' | |||
| Subtypes = | |||
| LMDDx = [[low grade papillary urothelial carcinoma]] with an inverted growth pattern | |||
| Stains = | |||
| IHC = Ki-67 -ve, CK20 -ve, p53 -ve (rarely +ve) | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[urothelium]] - usu. [[urinary bladder]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Inverted urothelial papilloma''', also '''inverted papilloma''', is a benign [[urothelium|urothelial]] lesion that may be confused with [[urothelial carcinoma]]. | '''Inverted urothelial papilloma''', also '''inverted papilloma''', is a benign [[urothelium|urothelial]] lesion that may be confused with [[urothelial carcinoma]]. | ||
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DDx: | DDx: | ||
*[[Low grade papillary urothelial carcinoma]] with an inverted growth pattern. | *[[Low grade papillary urothelial carcinoma]] with an inverted growth pattern. | ||
*[[Cystitis cystica]]. | |||
===Images=== | ===Images=== | ||
====Case 1==== | |||
<gallery> | <gallery> | ||
Image:Inverted_papilloma_high_mag.jpg | Inverted papilloma - high mag. (WC/Nephron) | Image:Inverted_papilloma_high_mag.jpg | Inverted papilloma - high mag. (WC/Nephron) | ||
Image:Inverted_papilloma_intermed_mag.jpg | Inverted papilloma - intermed. mag. (WC/Nephron) | Image:Inverted_papilloma_intermed_mag.jpg | Inverted papilloma - intermed. mag. (WC/Nephron) | ||
</gallery> | |||
====Case 2==== | |||
<gallery> | |||
Image: Bladder inverted papilloma histopathology (1).jpg | IUP. (WC/KGH) | |||
Image: Bladder inverted papilloma histopathology (2).jpg | IUP. (WC/KGH) | |||
Image: Bladder inverted papilloma histopathology (3).jpg | IUP. (WC/KGH) | |||
</gallery> | </gallery> | ||
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==See also== | ==See also== | ||
*[[Urothelium]]. | *[[Urothelium]]. | ||
*[[Urothelial papilloma]]. | |||
*[[Cystitis cystica]]. | *[[Cystitis cystica]]. | ||
==Sign out== | |||
<pre> | |||
Bladder Tumour, Transurthral Resection: | |||
- Inverted papilloma. | |||
</pre> | |||
===Micro=== | |||
The sections show urothelial mucosa with a densely packed urothelial nests with peripheral palisading. The cells of the urothelial nests are bland. Proliferative activity is not apparent. Definite papillae are absent. No exophytic component is apparent. | |||
==References== | ==References== | ||