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Difference between revisions of "Intraductal papilloma of the breast"
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Intraductal papilloma of the breast (view source)
Revision as of 21:18, 9 May 2016
, 21:18, 9 May 2016no edit summary
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| Tx = usually excision | | Tx = usually excision | ||
}} | }} | ||
'''Intraductal papilloma''', also '''papilloma''', is a relatively common benign [[breast pathology|pathology of the breast]]. | '''Intraductal papilloma of the breast''', also '''papilloma''' and '''[[intraductal papilloma]]''', is a relatively common benign [[breast pathology|pathology of the breast]]. | ||
==General== | ==General== | ||
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*Lacks florid hyperplasia.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | *Lacks florid hyperplasia.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | ||
*May degeneration and hyalinize to form a ''sclerosing papilloma''. | *May degeneration and hyalinize to form a ''sclerosing papilloma''. | ||
*When many ducts are involved the process is termed 'papillomatosis'. | |||
DDx: | DDx: | ||
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*Intraductal papilloma with [[atypical ductal hyperplasia]]. † | *Intraductal papilloma with [[atypical ductal hyperplasia]]. † | ||
*Intraductal papilloma with [[ductal carcinoma in situ]]. † | *Intraductal papilloma with [[ductal carcinoma in situ]]. † | ||
*[[Ductal carcinoma in situ]] - papillary variant | |||
*[[Invasive papillary carcinoma of the breast]]. | *[[Invasive papillary carcinoma of the breast]]. | ||
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Image:Intraductal papilloma histopathology (2) smooth muscle actin.JPG | IP - SMA. (WC/KGH) | Image:Intraductal papilloma histopathology (2) smooth muscle actin.JPG | IP - SMA. (WC/KGH) | ||
Image:Intraductal_papilloma_histopathology_(3)_p63.JPG | IP - p63 (WC/KGH) | Image:Intraductal_papilloma_histopathology_(3)_p63.JPG | IP - p63 (WC/KGH) | ||
Image:Breast IntraductalPapillomatosis LP CTR.jpg|Breast - Intraductal Papillomatosis with some usual type epithelial hyperplasia - Low power (SKB) | |||
Image:Breast IntraductalPapillomatosis MP2 CTR.jpg|Breast - Intraductal Papillomatosis with some usual type epithelial hyperplasia - Medium power (SKB) | |||
Image:Breast IntraductalPapilloma LP PA.JPG|Breast - Intraductal Papilloma - Low power (SKB) | |||
Image:Breast IntraductalPapilloma MP PA.JPG|Breast - Intraductal Papilloma - Medium power (SKB) | |||
Image: | Image:Breast IntraductalPapilloma HP PA.JPG|Breast - Intraductal Papilloma - High power (SKB) | ||
Image: | Image:Breast IntraductalPapilloma LP (2) PA.JPG|Breast - Intraductal Papilloma - Low power (SKB) | ||
Image:Breast IntraductalPapilloma Histiocytes MP PA.JPG|Breast - Intraductal Papilloma - Histiocytes - High power (SKB) | |||
</gallery> | </gallery> | ||
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Features:<ref name=pmid22612506>{{Cite journal | last1 = Furuya | first1 = C. | last2 = Kawano | first2 = H. | last3 = Yamanouchi | first3 = T. | last4 = Oga | first4 = A. | last5 = Ueda | first5 = J. | last6 = Takahashi | first6 = M. | title = Combined evaluation of CK5/6, ER, p63, and MUC3 for distinguishing breast intraductal papilloma from ductal carcinoma in situ. | journal = Pathol Int | volume = 62 | issue = 6 | pages = 381-90 | month = Jun | year = 2012 | doi = 10.1111/j.1440-1827.2012.02811.x | PMID = 22612506 }} | Features:<ref name=pmid22612506>{{Cite journal | last1 = Furuya | first1 = C. | last2 = Kawano | first2 = H. | last3 = Yamanouchi | first3 = T. | last4 = Oga | first4 = A. | last5 = Ueda | first5 = J. | last6 = Takahashi | first6 = M. | title = Combined evaluation of CK5/6, ER, p63, and MUC3 for distinguishing breast intraductal papilloma from ductal carcinoma in situ. | journal = Pathol Int | volume = 62 | issue = 6 | pages = 381-90 | month = Jun | year = 2012 | doi = 10.1111/j.1440-1827.2012.02811.x | PMID = 22612506 }} | ||
</ref> | </ref> | ||
*CK5/6 +ve. | *[[CK5/6]] +ve. | ||
*p63 +ve. | *[[p63]] +ve. | ||
*MUC3 weak. | *MUC3 weak. | ||
*ER weak. | *ER weak. | ||
**Strong in [[DCIS]]. | **Strong in [[DCIS]]. | ||
==Sign out== | |||
<pre> | |||
Right Breast, Partial Mastectomy: | |||
- Intraductal papilloma. | |||
- Proliferative fibrocystic changes. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
==See also== | ==See also== | ||
*[[Breast pathology]]. | *[[Breast pathology]]. | ||
*[[Papillary hidradenoma]]. | *[[Papillary hidradenoma]]. | ||
*[[Intraductal papilloma]]. | |||
==References== | ==References== | ||