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Difference between revisions of "Intestinal metaplasia of the stomach"
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Intestinal metaplasia of the stomach (view source)
Revision as of 20:54, 23 July 2013
, 20:54, 23 July 2013tweak
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| Caption = Intestinal metaplasia of the stomach. [[H&E stain]]. | | Caption = Intestinal metaplasia of the stomach. [[H&E stain]]. | ||
| Micro = | | Micro = goblet cells with foveolar epithelium | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = contaminant from the [[duodenum]], [[gastric dysplasia]], [[gastric carcinoma]] | | LMDDx = contaminant from the [[duodenum]], [[gastric dysplasia]], [[gastric carcinoma]] | ||
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*[[Gastric dysplasia]], intestinal type. | *[[Gastric dysplasia]], intestinal type. | ||
Image | ===Images=== | ||
<gallery> | |||
Image:Gastric_adenocarcinoma.jpg | Intestinal metaplasia in the stomach - crappy quality. (WC) | |||
</gallery> | |||
==Stains== | ==Stains== | ||
*Alcian blue (pH 2.5)/PAS +ve.<ref name=pmid14736279>{{Cite journal | last1 = Rivera-Hueto | first1 = F. | last2 = Lag-Asturiano | first2 = E. | last3 = Utrilla-Alcolea | first3 = JC. | last4 = Herrerías-Gutiérrez | first4 = JM. | title = Advanced gastric carcinoma with a complete intestinal metaplasia phenotype associated with early intestinal-type carcinoma. | journal = Arch Pathol Lab Med | volume = 128 | issue = 2 | pages = 218-21 | month = Feb | year = 2004 | doi = 10.1043/1543-2165(2004)128218:AGCWAC2.0.CO;2 | PMID = 14736279 }}</ref> | *Alcian blue (pH 2.5)/PAS +ve.<ref name=pmid14736279>{{Cite journal | last1 = Rivera-Hueto | first1 = F. | last2 = Lag-Asturiano | first2 = E. | last3 = Utrilla-Alcolea | first3 = JC. | last4 = Herrerías-Gutiérrez | first4 = JM. | title = Advanced gastric carcinoma with a complete intestinal metaplasia phenotype associated with early intestinal-type carcinoma. | journal = Arch Pathol Lab Med | volume = 128 | issue = 2 | pages = 218-21 | month = Feb | year = 2004 | doi = 10.1043/1543-2165(2004)128218:AGCWAC2.0.CO;2 | PMID = 14736279 }}</ref> | ||
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*Alican blue stain +ve.{{fact}} | *Alican blue stain +ve.{{fact}} | ||
Image | ===Image=== | ||
<gallery> | |||
Image:Barrett%27s_mucosa,_Alcian_blue_stain.jpg | Barrett's mucosa - Alcian blue stain. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
*CDX2 +ve (-ve in normal stomach).<ref name=pmid12477745>{{Cite journal | last1 = Walker | first1 = MM. | title = Is intestinal metaplasia of the stomach reversible? | journal = Gut | volume = 52 | issue = 1 | pages = 1-4 | month = Jan | year = 2003 | doi = | PMID = 12477745 | PMC = 1773527 | *CDX2 +ve (-ve in normal stomach).<ref name=pmid12477745>{{Cite journal | last1 = Walker | first1 = MM. | title = Is intestinal metaplasia of the stomach reversible? | journal = Gut | volume = 52 | issue = 1 | pages = 1-4 | month = Jan | year = 2003 | doi = | PMID = 12477745 | PMC = 1773527 | ||